{"id":1090,"date":"2022-12-12T11:53:03","date_gmt":"2022-12-12T16:53:03","guid":{"rendered":"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/chapter\/introduction-to-integumentary-system\/"},"modified":"2024-05-03T15:27:53","modified_gmt":"2024-05-03T19:27:53","slug":"introduction-to-integumentary-system","status":"publish","type":"chapter","link":"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/chapter\/introduction-to-integumentary-system\/","title":{"raw":"Introduction to Integumentary System","rendered":"Introduction to Integumentary System"},"content":{"raw":"<span style=\"color: #000000\">The integumentary system includes the skin, hair, nails, and [pb_glossary id=\"1434\"]sebaceous[\/pb_glossary] and sweat glands. It has important functions including thermoregulation, sensory functioning, ensuring fluid balance, serving as a protective barrier to external substances, and providing immune defense against foreign bodies.<\/span>\r\n\r\n<span style=\"color: #000000\">The integument can be an indicator of the client\u2019s general health status. For example, the integumentary system can signal other systemic functions of the body like [pb_glossary id=\"1436\"]diaphoresis[\/pb_glossary] during cardiac events, [pb_glossary id=\"1474\"]cyanosis[\/pb_glossary] related to respiratory insufficiency and other conditions, and [pb_glossary id=\"1476\"]pallor[\/pb_glossary] during times of stress and other conditions. As a nurse, it is important to hone your assessment skills and pay close attention to potential cues that may signal underlying concerns that require your intervention. See <strong>Figure 1<\/strong> for an anatomical overview of the integumentary system.<\/span>\r\n\r\n<img src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2022\/12\/Skin-Layer-300x273.png\" alt=\"The integumentary layers showing the epidermis, dermis, and fatty tissue, as well as blood vessels, follicle, oil gland, sweat gland and melanocytes.\" width=\"374\" height=\"340\" class=\"aligncenter wp-image-1078\" \/>\r\n\r\n<span style=\"color: #000000\"><strong>Figure 1:<\/strong> Integumentary system anatomy. <\/span>\r\n\r\n<span style=\"color: #000000\">(Image in public domain and adapted from the National Cancer Institute:<\/span> <a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:Anatomy_The_Skin_-_NCI_Visuals_Online.jpg\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikimedia.org\/wiki\/File:Anatomy_The_Skin_-_NCI_Visuals_Online.jpg<\/a>)\r\n\r\n&nbsp;\r\n\r\n<span style=\"color: #000000\">You have already learned about the anatomy and physiology of the integumentary system: for a quick overview see<\/span> <a href=\"https:\/\/youtu.be\/OxPlCkTKhzY\" target=\"_blank\" rel=\"noopener\">https:\/\/youtu.be\/OxPlCkTKhzY<\/a>\r\n\r\n<span style=\"color: #000000\">You need a basic understanding of disease-specific presentations to effectively interpret findings from your assessment. Be alert to signs and symptoms of greater systemic issues that may require further assessment and possibly immediate intervention. For example, Cullen\u2019s sign (<strong>Figure 2<\/strong>) is a serious concern: it appears as bruising and edema of the subcutaneous fatty tissue around the navel and can be an indication of acute pancreatic trauma and\/or internal bleeding. Certain skin symptoms can also prompt the use of personal protective equipment (PPE); for example, small flat red spots that appear on the face and spread down the body may be an indication of [pb_glossary id=\"1432\"]measles[\/pb_glossary] (<strong>Figure 3<\/strong>), necessitating airborne precautions.<\/span>\r\n\r\n<img src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Cullens_sign-300x195.jpg\" alt=\"A dark brown and red bruise on a swollen abdomen below the umbilicus.\" width=\"458\" height=\"298\" class=\"aligncenter wp-image-1079\" \/>\r\n\r\n<span style=\"color: #000000\"><strong>Figure 2:<\/strong> Cullen\u2019s sign.<\/span>\r\n\r\n<span style=\"color: #000000\">(Attribution: Photo by Herbert L. Fred, MD and Hendrik A. van Dijk - http:\/\/cnx.org\/content\/m14904\/latest\/, CC BY 2.0,<\/span> <a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=5038484\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikimedia.org\/w\/index.php?curid=5038484<\/a>)\r\n\r\n<img src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Measles_child_Philippines-scaled-1.jpg\" alt=\"Flat red dots on a child's face.\" width=\"447\" height=\"296\" class=\"aligncenter wp-image-1168\" \/>\r\n\r\n<span style=\"color: #000000\"><strong>Figure 3:<\/strong> Measles.<\/span>\r\n\r\n<span style=\"color: #000000\">(Attribution: This photo is in the public domain in the United States because it is a work prepared by an officer or employee of the United States Government as part of that person\u2019s official duties under the terms of Title 17, Chapter 1, Section 105 of the US Code.<\/span> <a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:Measles_child_Philippines.jpg\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikimedia.org\/wiki\/File:Measles_child_Philippines.jpg<\/a><span style=\"color: #000000\">)<\/span>\r\n\r\n<span style=\"color: #000000\">Contextualization of integumentary issues in relation to other symptomatology like fever, cough, and inflammation can provide insight into underlying conditions. <strong>Table 1<\/strong> provides some general descriptions related to the integument and underlying pathophysiology. With experience, you will learn to identify patterns, recognize cues, and begin to discriminate between [pb_glossary id=\"1492\"]benign[\/pb_glossary] skin conditions and skin conditions that require further investigation.<\/span>\r\n\r\n<span style=\"color: #000000\"><strong>Table 1:<\/strong> General descriptions of integument pathophysiology.<\/span>\r\n<table class=\"grid\" style=\"border-collapse: collapse;height: 3558px;width: 603px\" border=\"0\">\r\n<tbody>\r\n<tr class=\"shaded\" style=\"height: 15px\">\r\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<strong><span style=\"color: #000000\">Integumentary grouping<\/span><\/strong><\/td>\r\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<strong><span style=\"color: #000000\">Examples<\/span><\/strong><\/td>\r\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<strong><span style=\"color: #000000\">Common presentation<\/span><\/strong><\/td>\r\n<\/tr>\r\n<tr style=\"height: 15px\">\r\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\"><strong>Skin trauma<\/strong><\/span>\r\n\r\n<span style=\"color: #000000\">Trauma can affect a single or multiple layers of the skin as a result of injury or illness.<\/span><\/td>\r\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\">Burns, scars, cuts, tears of the skin, keloids (thick, raised scars).<\/span>\r\n\r\n<span style=\"color: #000000\"><img src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Keloid_Post_Surgical-300x200.jpg\" alt=\"A raised, thick scar.\" width=\"177\" height=\"118\" class=\"alignnone wp-image-1081\" \/><\/span>\r\n\r\n<span style=\"color: #000000\">Keloid.<\/span>\r\n\r\n<span style=\"color: #000000\">(Attribution: Photo by Htirgan - Own work, CC BY-SA 3.0, <a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=32782658\" target=\"_blank\" rel=\"noopener\" style=\"color: #000000\">https:\/\/commons.wikimedia.org\r\n\/w\/index.php?curid=32782658<\/a><\/span><\/td>\r\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\">Swelling, erythema, inflammation, bleeding, pain, blisters, peeling of skin, and sometimes darkened or lightened areas of skin with scars.<\/span><\/td>\r\n<\/tr>\r\n<tr style=\"height: 15px\">\r\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\"><strong>Infections<\/strong><\/span>\r\n\r\n<span style=\"color: #000000\">Bacterial, viral, fungal, and parasitic skin infections are caused by various pathogens and can range from mild to severe. Many skin infections require treatment.<\/span>\r\n\r\n<img src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Shingles-300x152.jpg\" alt=\"Coalesced patches of red lesions on the arm from the wrist to the upper arm.\" width=\"207\" height=\"105\" class=\"alignnone wp-image-1082\" \/>\r\n\r\n<span style=\"color: #000000\">[pb_glossary id=\"1426\"]Shingles[\/pb_glossary].<\/span>\r\n\r\n<span style=\"color: #000000\">(Attribution: Photo by James Heilman, MD - Own work, CC BY-SA 3.0,<\/span> <a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=14082247\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikimedia.org\r\n\/w\/index.php?curid=14082247<\/a><span style=\"color: #000000\">)<\/span><\/td>\r\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\">Viral: Human papillomavirus (HPV), herpes zoster virus, warts, COVID-19, shingles.<\/span>\r\n\r\n<span style=\"color: #000000\">Bacterial: Staphylococcus-aureus, Methicillin-resistant Staphylococcus aureus (MRSA), impetigo, cellulitis, boils, and abscesses.<\/span>\r\n\r\n<span style=\"color: #000000\">Fungal (typically skin and mucosal surfaces): Tinea corporis (ringworm), tinea pedis (athlete\u2019s foot), candidosis (yeast infection), nail fungus.<\/span>\r\n\r\n<span style=\"color: #000000\">Parasitic: Lice, bedbugs.<\/span>\r\n\r\n<span style=\"color: #000000\">Other stings and bites that can cause infection: Spider bites, ticks, animal bites.<\/span>\r\n\r\n<img src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/403px-Bullseye_rash_linked_to_Lyme_disease-202x300.jpg\" alt=\"A bull's eye rash.\" width=\"179\" height=\"266\" class=\"alignnone wp-image-1083\" \/>\r\n\r\n<span style=\"color: #000000\">Tick bite with bull\u2019s-eye rash (an early sign of Lyme disease).<\/span>\r\n\r\n<span style=\"color: #000000\">(Attribution: CDC \/ James Gathany - https:\/\/phil.cdc.gov\/Details.aspx?pid=9874, Public Domain,<\/span> <a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=91609710\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikimedia.org\r\n\/w\/index.php?curid=91609710<\/a><span style=\"color: #000000\">)<\/span><\/td>\r\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\">Viral: Some rashes can follow a [pb_glossary id=\"1428\"]dermatome[\/pb_glossary] (e.g., shingles, varicella, herpes simplex) with lesions, papules, or pain. They can appear in cluster\/closely grouped or as a single lesion, and can be generalized, regional, or asymmetrical presentation (i.e., rash on one side of the body).<\/span>\r\n\r\n<span style=\"color: #000000\">Bacterial: Odour, exudate, small red bumps increasing in size, fever, yellowish-brown crusts, redness, heat, swelling, tenderness, pain.<\/span>\r\n\r\n<span style=\"color: #000000\">Fungal: Deep erythema, swelling, itchiness, scaly, flaky patches, or loss of normal pigmentation of the skin causing discolouration.<\/span>\r\n\r\n<span style=\"color: #000000\">Parasitic: Itchiness, rash, regional lymphadenopathy (diseases of the lymph nodes resulting in enlarged lymph nodes).<\/span><\/td>\r\n<\/tr>\r\n<tr style=\"height: 15px\">\r\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\"><strong>Auto-immune and\/or inflammatory disorders causing lesions\/eruptions (acute and chronic)<\/strong><\/span>\r\n\r\n<span style=\"color: #000000\">Regional or generalized, may involve inflammation of the skin.<\/span><\/td>\r\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\">[pb_glossary id=\"1414\"]Psoriasis[\/pb_glossary], [pb_glossary id=\"1416\"]eczema[\/pb_glossary], [pb_glossary id=\"1418\"]seborrheic dermatitis[\/pb_glossary], [pb_glossary id=\"1420\"]vitiligo[\/pb_glossary], [pb_glossary id=\"1422\"]lupus[\/pb_glossary], [pb_glossary id=\"1424\"]alopecia[\/pb_glossary].<\/span>\r\n\r\n<img src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Allopecia_areata-300x225.jpg\" alt=\"A patch of missing hair on the back of the head.\" width=\"193\" height=\"145\" class=\"alignnone wp-image-1084\" \/>\r\n\r\n<span style=\"color: #000000\">Alopecia.<\/span>\r\n\r\n<span style=\"color: #000000\">(Attribution: Photo by Abbassyma at English Wikipedia - Transferred from en.wikipedia to Commons, Public Domain,<\/span> <a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=3121007\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikimedia.org\r\n\/w\/index.php?curid=3121007<\/a><span style=\"color: #000000\">)<\/span><\/td>\r\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\">Eczema (scaling, itching, ill-defined), psoriasis ([pb_glossary id=\"1412\"]well-demarcated[\/pb_glossary], scaly plaques), vitiligo (depigmentation, patchy loss of skin colour, premature whitening of hair), alopecia (hair loss).<\/span><\/td>\r\n<\/tr>\r\n<tr style=\"height: 15px\">\r\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\"><strong>Metabolic and nutritional disorders<\/strong><\/span>\r\n\r\n<span style=\"color: #000000\">Poor nutrition or absorption issues can lead to vitamin deficiencies. Excess vitamins can also lead to cutaneous abnormalities.<\/span><\/td>\r\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\">Vitamin A, C, D, E, K, B1, B2, B3, B6, B9, B12, iron, zinc, and selenium deficiencies.<\/span>\r\n\r\n<span style=\"color: #000000\">Vitamin A, E, and selenium excess.<\/span><\/td>\r\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\">Varies depending on metabolic\/nutritional disorders, e.g., dermatitis, flushing, hyperpigmentation, white spots.<\/span><\/td>\r\n<\/tr>\r\n<tr style=\"height: 15px\">\r\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\"><strong>Vascular disorders<\/strong><\/span>\r\n\r\n<span style=\"color: #000000\">Cutaneous vascular disorders commonly involve arteries, veins, and\/or lymphatic vessels.<\/span><\/td>\r\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\">Ulcers, [pb_glossary id=\"1410\"]cherry angiomas[\/pb_glossary], venous insufficiency.<\/span>\r\n\r\n<img src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Chronic_venous_insufficiency__Venous_ulcer-300x204.jpg\" alt=\"A large open sore on the posterior side of the ankle\/leg with white and brown discolouration.\" width=\"197\" height=\"134\" class=\"alignnone wp-image-1085\" \/>\r\n\r\n<span style=\"color: #000000\">Venous insufficiency.<\/span>\r\n\r\n<span style=\"color: #000000\">(Attribution: Photo by Ashashyou - Own work, CC BY-SA 4.0,<\/span> <a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=122884459\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikimedia.org\r\n\/w\/index.php?curid=122884459<\/a><span style=\"color: #000000\">)<\/span>\r\n\r\n<img src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Cherry-angioma-IMG_3443-scaled-1.jpg\" alt=\"Several small red dots on the abdomen.\" width=\"144\" height=\"192\" class=\"alignnone wp-image-1548\" \/>\r\n\r\n<span style=\"color: #000000\">Cherry angioma.<\/span><\/td>\r\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\">Varies depending on venous insufficiency (flooding of fluid to the skin due to inadequate venous return) or arterial deprivation (deprivation of nutrients to the skin due to poor arterial perfusion).<\/span>\r\n\r\n<span style=\"color: #000000\">Variations such as cherry angiomas are not harmful. They can begin small and then grow in size, become slightly raised, and multiply over time.<\/span><\/td>\r\n<\/tr>\r\n<tr style=\"height: 15px\">\r\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\"><strong>Psychological and neurological disorders<\/strong><\/span>\r\n\r\n<span style=\"color: #000000\">Involve interactions between the mind and skin.<\/span><\/td>\r\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\">Persistent [pb_glossary id=\"1406\"]pruritus[\/pb_glossary] and [pb_glossary id=\"1408\"]prurigo[\/pb_glossary], neuropathic pain (often related to shingles), trichotillomania (a psychiatric condition resulting in compulsive hair pulling).<\/span><\/td>\r\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\">Irresistible itching and scratching, urge to scratch exacerbated by anxiety, skin picking, recurrent pulling out of hair.<\/span><\/td>\r\n<\/tr>\r\n<tr style=\"height: 15px\">\r\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\"><strong>Systemic disorders<\/strong><\/span>\r\n\r\n<span style=\"color: #000000\">The integumentary system can be involved in clinical manifestation of some systemic disorders.<\/span><\/td>\r\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\">Gout, arthritis, Addison disease, Cushing syndrome, thyroid disease, chronic liver disease, hepatitis, diabetic ulcers.<\/span><\/td>\r\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\">Varies depending on the <\/span><span style=\"color: #000000\">underlying systemic disorder.<\/span>\r\n\r\n<img src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Podagra-300x190.jpg\" alt=\"Two feet with a black arrow pointing at a reddened area on the left foot.\" width=\"182\" height=\"115\" class=\"alignnone wp-image-1087\" \/>\r\n\r\n<span style=\"color: #000000\">Gout.<\/span>\r\n\r\n<span style=\"color: #000000\">(Attribution: Photo by Gonzos <\/span><span style=\"color: #000000\">ft - Own work, CC BY 3.0 de,<\/span> <a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=10868917\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikime<\/a>\r\n\r\n<a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=10868917\" target=\"_blank\" rel=\"noopener\">dia.org\/w\/index.php?curid=10868917<\/a><span style=\"color: #000000\">)<\/span><\/td>\r\n<\/tr>\r\n<tr style=\"height: 15px\">\r\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\"><strong>Neoplastics (abnormal growths) and cancer\u00a0<\/strong><\/span>\r\n\r\n<span style=\"color: #000000\">Benign [pb_glossary id=\"1394\"]cutaneous[\/pb_glossary] [pb_glossary id=\"1396\"]neoplasms[\/pb_glossary] are very common. Some abnormal growths are benign (non-cancerous). However, some neoplasms become [pb_glossary id=\"1430\"]malignant[\/pb_glossary] and require intervention.\u00a0<\/span><\/td>\r\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\">Benign: Freckles, [pb_glossary id=\"1398\"]lentigo[\/pb_glossary], [pb_glossary id=\"1400\"]caf\u00e9-au-lait spots[\/pb_glossary], [pb_glossary id=\"1482\"]nevi[\/pb_glossary], [pb_glossary id=\"1402\"]seborrheic keratosis[\/pb_glossary], wart, [pb_glossary id=\"1404\"]cutaneous cysts[\/pb_glossary].<\/span>\r\n\r\n<span style=\"color: #000000\">Malignant: [pb_glossary id=\"1484\"]Atypical nevi[\/pb_glossary], [pb_glossary id=\"1486\"]basal cell carcinoma[\/pb_glossary], [pb_glossary id=\"1488\"]squamous cell carcinoma[\/pb_glossary], [pb_glossary id=\"1490\"]melanoma[\/pb_glossary].<\/span>\r\n\r\n<span style=\"color: #000000\"><img src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/cherry-angioma-and-seborrheic-keratosis-IMG_0214JL-scaled-1.jpg\" alt=\"A dark brown raised lesion that is waxy with slight bumps throughout.\" width=\"173\" height=\"129\" class=\"alignnone wp-image-1175\" \/><\/span>\r\n\r\n<span style=\"color: #000000\">Seborrheic keratosis (the large brown raised lesion).<\/span><\/td>\r\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\">Varies depending on the underlying cause, e.g., spots on the skin, palpable mass, depression of the skin.<\/span>\r\n\r\n<span style=\"color: #000000\">Basal cell carcinoma.<\/span>\r\n\r\n<img src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Basal_cell_carcinoma2-298x300.jpg\" alt=\"A reddened lesion on the nose with a dark area on the superior edge of the lesion.\" width=\"159\" height=\"160\" class=\"alignnone wp-image-1089\" \/>\r\n\r\n<span style=\"color: #000000\">(Attribution: Photo by James Heilman, MD - Own work, CC BY 3.0,<\/span> <a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=6827823\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikimedia.<\/a>\r\n\r\n<a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=6827823\" target=\"_blank\" rel=\"noopener\">org\/w\/index.php?curid=6827823<\/a><span style=\"color: #000000\">)<\/span><\/td>\r\n<\/tr>\r\n<tr style=\"height: 15px\">\r\n<td style=\"width: 234.56px;height: 10px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\"><strong>Skin disorders caused by external agents<\/strong><\/span>\r\n\r\n<span style=\"color: #000000\">Cutaneous adverse reactions can occur because of reactions to drugs or other external agents. Adverse reactions can also occur from heat and cold exposures.<\/span><\/td>\r\n<td style=\"width: 228.634px;height: 10px;vertical-align: top\">&nbsp;\r\n<p style=\"text-align: left\"><span style=\"color: #000000\">Steven-Johnson syndrome and\r\ntoxic epidermal necrolysis are rare life-threatening skin disorders where the skin peels and blisters often caused by a medications and infections. Toxic erythema from chemotherapy is a skin reaction including eruptions of red\/purple rash and plaques.\r\nPhotosensitivity is a skin sensitivity when exposed to the sun c<\/span><span style=\"color: #000000;font-family: inherit;font-size: inherit\">aused by medications like chemotherapy drugs, HIV medications and antibiotics, frostbite.<\/span><\/p>\r\n<\/td>\r\n<td style=\"width: 200px;height: 10px;vertical-align: top\">&nbsp;\r\n\r\n<span style=\"color: #000000\">Skin reactions like rashes that start after exposure to external agents like medications.<\/span><\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<div align=\"left\"><\/div>\r\n<span style=\"color: #000000\">*genetic disorders not listed<\/span>\r\n\r\n&nbsp;\r\n<div class=\"textbox textbox--examples\"><header class=\"textbox__header\">\r\n<h2 class=\"textbox__title\" style=\"text-align: center\"><strong>Clinical Tip<\/strong><\/h2>\r\n<\/header>\r\n<div class=\"textbox__content\">\r\n\r\n<span style=\"color: #000000\">Did you know that some dermatological conditions are emergencies? For example, necrotizing fasciitis (a rare bacterial infection also known as flesh-eating disease) can spread very quickly throughout the body, at a rate of 1 inch per hour. Symptoms include erythema, warmth to the touch, swelling, severe pain, and fever. If not treated immediately, it can lead to [pb_glossary id=\"1384\"]sepsis[\/pb_glossary], [pb_glossary id=\"1386\"]shock[\/pb_glossary], organ failure, and even death. As a nurse, you must report these findings to the physician or nurse practitioner so immediate treatment can be started.<\/span>\r\n\r\n<\/div>\r\n<\/div>\r\n<div class=\"textbox textbox--exercises\"><header class=\"textbox__header\">\r\n<h2 class=\"textbox__title\" style=\"text-align: center\"><strong>Knowledge Bites: Pathophysiology<\/strong><\/h2>\r\n<\/header>\r\n<div class=\"textbox__content\">\r\n\r\n<span style=\"color: #000000\">How do you distinguish between common viral and bacterial infections? Common characteristics of a bacterial infection are inflammation, [pb_glossary id=\"1382\"]exudate [\/pb_glossary] (such as pus), erythema, swelling, pain, odour. Common characteristics of a viral infection are a grouping\/cluster of lesions, generally asymmetrical (one side of body), and specific regions on the body (e.g., mouth, nose, feet, hands).<\/span>\r\n\r\n<\/div>\r\n<\/div>\r\n<h2><span>Activity: Check Your Understanding<\/span><\/h2>\r\n<span>Name the integument pathophysiology images:<\/span>\r\n\r\n&nbsp;\r\n\r\n<span>[h5p id=\"76\"]<\/span>","rendered":"<p><span style=\"color: #000000\">The integumentary system includes the skin, hair, nails, and <button class=\"glossary-term\" aria-describedby=\"1090-1434\">sebaceous<\/button> and sweat glands. It has important functions including thermoregulation, sensory functioning, ensuring fluid balance, serving as a protective barrier to external substances, and providing immune defense against foreign bodies.<\/span><\/p>\n<p><span style=\"color: #000000\">The integument can be an indicator of the client\u2019s general health status. For example, the integumentary system can signal other systemic functions of the body like <button class=\"glossary-term\" aria-describedby=\"1090-1436\">diaphoresis<\/button> during cardiac events, <button class=\"glossary-term\" aria-describedby=\"1090-1474\">cyanosis<\/button> related to respiratory insufficiency and other conditions, and <button class=\"glossary-term\" aria-describedby=\"1090-1476\">pallor<\/button> during times of stress and other conditions. As a nurse, it is important to hone your assessment skills and pay close attention to potential cues that may signal underlying concerns that require your intervention. See <strong>Figure 1<\/strong> for an anatomical overview of the integumentary system.<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2022\/12\/Skin-Layer-300x273.png\" alt=\"The integumentary layers showing the epidermis, dermis, and fatty tissue, as well as blood vessels, follicle, oil gland, sweat gland and melanocytes.\" width=\"374\" height=\"340\" class=\"aligncenter wp-image-1078\" srcset=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2022\/12\/Skin-Layer-300x273.png 300w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2022\/12\/Skin-Layer-768x699.png 768w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2022\/12\/Skin-Layer-65x59.png 65w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2022\/12\/Skin-Layer-225x205.png 225w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2022\/12\/Skin-Layer-350x318.png 350w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2022\/12\/Skin-Layer.png 941w\" sizes=\"auto, (max-width: 374px) 100vw, 374px\" \/><\/p>\n<p><span style=\"color: #000000\"><strong>Figure 1:<\/strong> Integumentary system anatomy. <\/span><\/p>\n<p><span style=\"color: #000000\">(Image in public domain and adapted from the National Cancer Institute:<\/span> <a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:Anatomy_The_Skin_-_NCI_Visuals_Online.jpg\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikimedia.org\/wiki\/File:Anatomy_The_Skin_-_NCI_Visuals_Online.jpg<\/a>)<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #000000\">You have already learned about the anatomy and physiology of the integumentary system: for a quick overview see<\/span> <a href=\"https:\/\/youtu.be\/OxPlCkTKhzY\" target=\"_blank\" rel=\"noopener\">https:\/\/youtu.be\/OxPlCkTKhzY<\/a><\/p>\n<p><span style=\"color: #000000\">You need a basic understanding of disease-specific presentations to effectively interpret findings from your assessment. Be alert to signs and symptoms of greater systemic issues that may require further assessment and possibly immediate intervention. For example, Cullen\u2019s sign (<strong>Figure 2<\/strong>) is a serious concern: it appears as bruising and edema of the subcutaneous fatty tissue around the navel and can be an indication of acute pancreatic trauma and\/or internal bleeding. Certain skin symptoms can also prompt the use of personal protective equipment (PPE); for example, small flat red spots that appear on the face and spread down the body may be an indication of <button class=\"glossary-term\" aria-describedby=\"1090-1432\">measles<\/button> (<strong>Figure 3<\/strong>), necessitating airborne precautions.<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Cullens_sign-300x195.jpg\" alt=\"A dark brown and red bruise on a swollen abdomen below the umbilicus.\" width=\"458\" height=\"298\" class=\"aligncenter wp-image-1079\" srcset=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Cullens_sign-300x195.jpg 300w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Cullens_sign-65x42.jpg 65w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Cullens_sign-225x146.jpg 225w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Cullens_sign-350x227.jpg 350w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Cullens_sign.jpg 561w\" sizes=\"auto, (max-width: 458px) 100vw, 458px\" \/><\/p>\n<p><span style=\"color: #000000\"><strong>Figure 2:<\/strong> Cullen\u2019s sign.<\/span><\/p>\n<p><span style=\"color: #000000\">(Attribution: Photo by Herbert L. Fred, MD and Hendrik A. van Dijk &#8211; http:\/\/cnx.org\/content\/m14904\/latest\/, CC BY 2.0,<\/span> <a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=5038484\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikimedia.org\/w\/index.php?curid=5038484<\/a>)<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Measles_child_Philippines-scaled-1.jpg\" alt=\"Flat red dots on a child's face.\" width=\"447\" height=\"296\" class=\"aligncenter wp-image-1168\" \/><\/p>\n<p><span style=\"color: #000000\"><strong>Figure 3:<\/strong> Measles.<\/span><\/p>\n<p><span style=\"color: #000000\">(Attribution: This photo is in the public domain in the United States because it is a work prepared by an officer or employee of the United States Government as part of that person\u2019s official duties under the terms of Title 17, Chapter 1, Section 105 of the US Code.<\/span> <a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:Measles_child_Philippines.jpg\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikimedia.org\/wiki\/File:Measles_child_Philippines.jpg<\/a><span style=\"color: #000000\">)<\/span><\/p>\n<p><span style=\"color: #000000\">Contextualization of integumentary issues in relation to other symptomatology like fever, cough, and inflammation can provide insight into underlying conditions. <strong>Table 1<\/strong> provides some general descriptions related to the integument and underlying pathophysiology. With experience, you will learn to identify patterns, recognize cues, and begin to discriminate between <button class=\"glossary-term\" aria-describedby=\"1090-1492\">benign<\/button> skin conditions and skin conditions that require further investigation.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Table 1:<\/strong> General descriptions of integument pathophysiology.<\/span><\/p>\n<table class=\"grid\" style=\"border-collapse: collapse;height: 3558px;width: 603px\">\n<tbody>\n<tr class=\"shaded\" style=\"height: 15px\">\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><strong><span style=\"color: #000000\">Integumentary grouping<\/span><\/strong><\/td>\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><strong><span style=\"color: #000000\">Examples<\/span><\/strong><\/td>\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><strong><span style=\"color: #000000\">Common presentation<\/span><\/strong><\/td>\n<\/tr>\n<tr style=\"height: 15px\">\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\"><strong>Skin trauma<\/strong><\/span><\/p>\n<p><span style=\"color: #000000\">Trauma can affect a single or multiple layers of the skin as a result of injury or illness.<\/span><\/td>\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\">Burns, scars, cuts, tears of the skin, keloids (thick, raised scars).<\/span><\/p>\n<p><span style=\"color: #000000\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Keloid_Post_Surgical-300x200.jpg\" alt=\"A raised, thick scar.\" width=\"177\" height=\"118\" class=\"alignnone wp-image-1081\" srcset=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Keloid_Post_Surgical-300x200.jpg 300w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Keloid_Post_Surgical-768x512.jpg 768w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Keloid_Post_Surgical-65x43.jpg 65w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Keloid_Post_Surgical-225x150.jpg 225w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Keloid_Post_Surgical-350x233.jpg 350w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Keloid_Post_Surgical.jpg 800w\" sizes=\"auto, (max-width: 177px) 100vw, 177px\" \/><\/span><\/p>\n<p><span style=\"color: #000000\">Keloid.<\/span><\/p>\n<p><span style=\"color: #000000\">(Attribution: Photo by Htirgan &#8211; Own work, CC BY-SA 3.0, <a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=32782658\" target=\"_blank\" rel=\"noopener\" style=\"color: #000000\">https:\/\/commons.wikimedia.org<br \/>\n\/w\/index.php?curid=32782658<\/a><\/span><\/td>\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\">Swelling, erythema, inflammation, bleeding, pain, blisters, peeling of skin, and sometimes darkened or lightened areas of skin with scars.<\/span><\/td>\n<\/tr>\n<tr style=\"height: 15px\">\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\"><strong>Infections<\/strong><\/span><\/p>\n<p><span style=\"color: #000000\">Bacterial, viral, fungal, and parasitic skin infections are caused by various pathogens and can range from mild to severe. Many skin infections require treatment.<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Shingles-300x152.jpg\" alt=\"Coalesced patches of red lesions on the arm from the wrist to the upper arm.\" width=\"207\" height=\"105\" class=\"alignnone wp-image-1082\" srcset=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Shingles-300x152.jpg 300w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Shingles-768x388.jpg 768w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Shingles-65x33.jpg 65w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Shingles-225x114.jpg 225w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Shingles-350x177.jpg 350w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Shingles.jpg 800w\" sizes=\"auto, (max-width: 207px) 100vw, 207px\" \/><\/p>\n<p><span style=\"color: #000000\"><button class=\"glossary-term\" aria-describedby=\"1090-1426\">Shingles<\/button>.<\/span><\/p>\n<p><span style=\"color: #000000\">(Attribution: Photo by James Heilman, MD &#8211; Own work, CC BY-SA 3.0,<\/span> <a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=14082247\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikimedia.org<br \/>\n\/w\/index.php?curid=14082247<\/a><span style=\"color: #000000\">)<\/span><\/td>\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\">Viral: Human papillomavirus (HPV), herpes zoster virus, warts, COVID-19, shingles.<\/span><\/p>\n<p><span style=\"color: #000000\">Bacterial: Staphylococcus-aureus, Methicillin-resistant Staphylococcus aureus (MRSA), impetigo, cellulitis, boils, and abscesses.<\/span><\/p>\n<p><span style=\"color: #000000\">Fungal (typically skin and mucosal surfaces): Tinea corporis (ringworm), tinea pedis (athlete\u2019s foot), candidosis (yeast infection), nail fungus.<\/span><\/p>\n<p><span style=\"color: #000000\">Parasitic: Lice, bedbugs.<\/span><\/p>\n<p><span style=\"color: #000000\">Other stings and bites that can cause infection: Spider bites, ticks, animal bites.<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/403px-Bullseye_rash_linked_to_Lyme_disease-202x300.jpg\" alt=\"A bull's eye rash.\" width=\"179\" height=\"266\" class=\"alignnone wp-image-1083\" srcset=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/403px-Bullseye_rash_linked_to_Lyme_disease-202x300.jpg 202w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/403px-Bullseye_rash_linked_to_Lyme_disease-65x97.jpg 65w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/403px-Bullseye_rash_linked_to_Lyme_disease-225x334.jpg 225w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/403px-Bullseye_rash_linked_to_Lyme_disease-350x520.jpg 350w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/403px-Bullseye_rash_linked_to_Lyme_disease.jpg 403w\" sizes=\"auto, (max-width: 179px) 100vw, 179px\" \/><\/p>\n<p><span style=\"color: #000000\">Tick bite with bull\u2019s-eye rash (an early sign of Lyme disease).<\/span><\/p>\n<p><span style=\"color: #000000\">(Attribution: CDC \/ James Gathany &#8211; https:\/\/phil.cdc.gov\/Details.aspx?pid=9874, Public Domain,<\/span> <a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=91609710\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikimedia.org<br \/>\n\/w\/index.php?curid=91609710<\/a><span style=\"color: #000000\">)<\/span><\/td>\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\">Viral: Some rashes can follow a <button class=\"glossary-term\" aria-describedby=\"1090-1428\">dermatome<\/button> (e.g., shingles, varicella, herpes simplex) with lesions, papules, or pain. They can appear in cluster\/closely grouped or as a single lesion, and can be generalized, regional, or asymmetrical presentation (i.e., rash on one side of the body).<\/span><\/p>\n<p><span style=\"color: #000000\">Bacterial: Odour, exudate, small red bumps increasing in size, fever, yellowish-brown crusts, redness, heat, swelling, tenderness, pain.<\/span><\/p>\n<p><span style=\"color: #000000\">Fungal: Deep erythema, swelling, itchiness, scaly, flaky patches, or loss of normal pigmentation of the skin causing discolouration.<\/span><\/p>\n<p><span style=\"color: #000000\">Parasitic: Itchiness, rash, regional lymphadenopathy (diseases of the lymph nodes resulting in enlarged lymph nodes).<\/span><\/td>\n<\/tr>\n<tr style=\"height: 15px\">\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\"><strong>Auto-immune and\/or inflammatory disorders causing lesions\/eruptions (acute and chronic)<\/strong><\/span><\/p>\n<p><span style=\"color: #000000\">Regional or generalized, may involve inflammation of the skin.<\/span><\/td>\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\"><button class=\"glossary-term\" aria-describedby=\"1090-1414\">Psoriasis<\/button>, <button class=\"glossary-term\" aria-describedby=\"1090-1416\">eczema<\/button>, <button class=\"glossary-term\" aria-describedby=\"1090-1418\">seborrheic dermatitis<\/button>, <button class=\"glossary-term\" aria-describedby=\"1090-1420\">vitiligo<\/button>, <button class=\"glossary-term\" aria-describedby=\"1090-1422\">lupus<\/button>, <button class=\"glossary-term\" aria-describedby=\"1090-1424\">alopecia<\/button>.<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Allopecia_areata-300x225.jpg\" alt=\"A patch of missing hair on the back of the head.\" width=\"193\" height=\"145\" class=\"alignnone wp-image-1084\" srcset=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Allopecia_areata-300x225.jpg 300w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Allopecia_areata-768x576.jpg 768w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Allopecia_areata-65x49.jpg 65w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Allopecia_areata-225x169.jpg 225w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Allopecia_areata-350x263.jpg 350w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/800px-Allopecia_areata.jpg 800w\" sizes=\"auto, (max-width: 193px) 100vw, 193px\" \/><\/p>\n<p><span style=\"color: #000000\">Alopecia.<\/span><\/p>\n<p><span style=\"color: #000000\">(Attribution: Photo by Abbassyma at English Wikipedia &#8211; Transferred from en.wikipedia to Commons, Public Domain,<\/span> <a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=3121007\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikimedia.org<br \/>\n\/w\/index.php?curid=3121007<\/a><span style=\"color: #000000\">)<\/span><\/td>\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\">Eczema (scaling, itching, ill-defined), psoriasis (<button class=\"glossary-term\" aria-describedby=\"1090-1412\">well-demarcated<\/button>, scaly plaques), vitiligo (depigmentation, patchy loss of skin colour, premature whitening of hair), alopecia (hair loss).<\/span><\/td>\n<\/tr>\n<tr style=\"height: 15px\">\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\"><strong>Metabolic and nutritional disorders<\/strong><\/span><\/p>\n<p><span style=\"color: #000000\">Poor nutrition or absorption issues can lead to vitamin deficiencies. Excess vitamins can also lead to cutaneous abnormalities.<\/span><\/td>\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\">Vitamin A, C, D, E, K, B1, B2, B3, B6, B9, B12, iron, zinc, and selenium deficiencies.<\/span><\/p>\n<p><span style=\"color: #000000\">Vitamin A, E, and selenium excess.<\/span><\/td>\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\">Varies depending on metabolic\/nutritional disorders, e.g., dermatitis, flushing, hyperpigmentation, white spots.<\/span><\/td>\n<\/tr>\n<tr style=\"height: 15px\">\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\"><strong>Vascular disorders<\/strong><\/span><\/p>\n<p><span style=\"color: #000000\">Cutaneous vascular disorders commonly involve arteries, veins, and\/or lymphatic vessels.<\/span><\/td>\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\">Ulcers, <button class=\"glossary-term\" aria-describedby=\"1090-1410\">cherry angiomas<\/button>, venous insufficiency.<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Chronic_venous_insufficiency__Venous_ulcer-300x204.jpg\" alt=\"A large open sore on the posterior side of the ankle\/leg with white and brown discolouration.\" width=\"197\" height=\"134\" class=\"alignnone wp-image-1085\" srcset=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Chronic_venous_insufficiency__Venous_ulcer-300x204.jpg 300w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Chronic_venous_insufficiency__Venous_ulcer-768x521.jpg 768w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Chronic_venous_insufficiency__Venous_ulcer-65x44.jpg 65w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Chronic_venous_insufficiency__Venous_ulcer-225x153.jpg 225w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Chronic_venous_insufficiency__Venous_ulcer-350x238.jpg 350w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Chronic_venous_insufficiency__Venous_ulcer.jpg 800w\" sizes=\"auto, (max-width: 197px) 100vw, 197px\" \/><\/p>\n<p><span style=\"color: #000000\">Venous insufficiency.<\/span><\/p>\n<p><span style=\"color: #000000\">(Attribution: Photo by Ashashyou &#8211; Own work, CC BY-SA 4.0,<\/span> <a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=122884459\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikimedia.org<br \/>\n\/w\/index.php?curid=122884459<\/a><span style=\"color: #000000\">)<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Cherry-angioma-IMG_3443-scaled-1.jpg\" alt=\"Several small red dots on the abdomen.\" width=\"144\" height=\"192\" class=\"alignnone wp-image-1548\" \/><\/p>\n<p><span style=\"color: #000000\">Cherry angioma.<\/span><\/td>\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\">Varies depending on venous insufficiency (flooding of fluid to the skin due to inadequate venous return) or arterial deprivation (deprivation of nutrients to the skin due to poor arterial perfusion).<\/span><\/p>\n<p><span style=\"color: #000000\">Variations such as cherry angiomas are not harmful. They can begin small and then grow in size, become slightly raised, and multiply over time.<\/span><\/td>\n<\/tr>\n<tr style=\"height: 15px\">\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\"><strong>Psychological and neurological disorders<\/strong><\/span><\/p>\n<p><span style=\"color: #000000\">Involve interactions between the mind and skin.<\/span><\/td>\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\">Persistent <button class=\"glossary-term\" aria-describedby=\"1090-1406\">pruritus<\/button> and <button class=\"glossary-term\" aria-describedby=\"1090-1408\">prurigo<\/button>, neuropathic pain (often related to shingles), trichotillomania (a psychiatric condition resulting in compulsive hair pulling).<\/span><\/td>\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\">Irresistible itching and scratching, urge to scratch exacerbated by anxiety, skin picking, recurrent pulling out of hair.<\/span><\/td>\n<\/tr>\n<tr style=\"height: 15px\">\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\"><strong>Systemic disorders<\/strong><\/span><\/p>\n<p><span style=\"color: #000000\">The integumentary system can be involved in clinical manifestation of some systemic disorders.<\/span><\/td>\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\">Gout, arthritis, Addison disease, Cushing syndrome, thyroid disease, chronic liver disease, hepatitis, diabetic ulcers.<\/span><\/td>\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\">Varies depending on the <\/span><span style=\"color: #000000\">underlying systemic disorder.<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Podagra-300x190.jpg\" alt=\"Two feet with a black arrow pointing at a reddened area on the left foot.\" width=\"182\" height=\"115\" class=\"alignnone wp-image-1087\" srcset=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Podagra-300x190.jpg 300w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Podagra-65x41.jpg 65w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Podagra-225x142.jpg 225w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Podagra-350x221.jpg 350w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Podagra.jpg 640w\" sizes=\"auto, (max-width: 182px) 100vw, 182px\" \/><\/p>\n<p><span style=\"color: #000000\">Gout.<\/span><\/p>\n<p><span style=\"color: #000000\">(Attribution: Photo by Gonzos <\/span><span style=\"color: #000000\">ft &#8211; Own work, CC BY 3.0 de,<\/span> <a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=10868917\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikime<\/a><\/p>\n<p><a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=10868917\" target=\"_blank\" rel=\"noopener\">dia.org\/w\/index.php?curid=10868917<\/a><span style=\"color: #000000\">)<\/span><\/td>\n<\/tr>\n<tr style=\"height: 15px\">\n<td style=\"width: 234.56px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\"><strong>Neoplastics (abnormal growths) and cancer\u00a0<\/strong><\/span><\/p>\n<p><span style=\"color: #000000\">Benign <button class=\"glossary-term\" aria-describedby=\"1090-1394\">cutaneous<\/button> <button class=\"glossary-term\" aria-describedby=\"1090-1396\">neoplasms<\/button> are very common. Some abnormal growths are benign (non-cancerous). However, some neoplasms become <button class=\"glossary-term\" aria-describedby=\"1090-1430\">malignant<\/button> and require intervention.\u00a0<\/span><\/td>\n<td style=\"width: 228.634px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\">Benign: Freckles, <button class=\"glossary-term\" aria-describedby=\"1090-1398\">lentigo<\/button>, <button class=\"glossary-term\" aria-describedby=\"1090-1400\">caf\u00e9-au-lait spots<\/button>, <button class=\"glossary-term\" aria-describedby=\"1090-1482\">nevi<\/button>, <button class=\"glossary-term\" aria-describedby=\"1090-1402\">seborrheic keratosis<\/button>, wart, <button class=\"glossary-term\" aria-describedby=\"1090-1404\">cutaneous cysts<\/button>.<\/span><\/p>\n<p><span style=\"color: #000000\">Malignant: <button class=\"glossary-term\" aria-describedby=\"1090-1484\">Atypical nevi<\/button>, <button class=\"glossary-term\" aria-describedby=\"1090-1486\">basal cell carcinoma<\/button>, <button class=\"glossary-term\" aria-describedby=\"1090-1488\">squamous cell carcinoma<\/button>, <button class=\"glossary-term\" aria-describedby=\"1090-1490\">melanoma<\/button>.<\/span><\/p>\n<p><span style=\"color: #000000\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/cherry-angioma-and-seborrheic-keratosis-IMG_0214JL-scaled-1.jpg\" alt=\"A dark brown raised lesion that is waxy with slight bumps throughout.\" width=\"173\" height=\"129\" class=\"alignnone wp-image-1175\" \/><\/span><\/p>\n<p><span style=\"color: #000000\">Seborrheic keratosis (the large brown raised lesion).<\/span><\/td>\n<td style=\"width: 200px;height: 15px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\">Varies depending on the underlying cause, e.g., spots on the skin, palpable mass, depression of the skin.<\/span><\/p>\n<p><span style=\"color: #000000\">Basal cell carcinoma.<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Basal_cell_carcinoma2-298x300.jpg\" alt=\"A reddened lesion on the nose with a dark area on the superior edge of the lesion.\" width=\"159\" height=\"160\" class=\"alignnone wp-image-1089\" srcset=\"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Basal_cell_carcinoma2-298x300.jpg 298w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Basal_cell_carcinoma2-150x150.jpg 150w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Basal_cell_carcinoma2-65x65.jpg 65w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Basal_cell_carcinoma2-225x227.jpg 225w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Basal_cell_carcinoma2-350x352.jpg 350w, https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-content\/uploads\/sites\/421\/2024\/05\/Basal_cell_carcinoma2.jpg 595w\" sizes=\"auto, (max-width: 159px) 100vw, 159px\" \/><\/p>\n<p><span style=\"color: #000000\">(Attribution: Photo by James Heilman, MD &#8211; Own work, CC BY 3.0,<\/span> <a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=6827823\" target=\"_blank\" rel=\"noopener\">https:\/\/commons.wikimedia.<\/a><\/p>\n<p><a href=\"https:\/\/commons.wikimedia.org\/w\/index.php?curid=6827823\" target=\"_blank\" rel=\"noopener\">org\/w\/index.php?curid=6827823<\/a><span style=\"color: #000000\">)<\/span><\/td>\n<\/tr>\n<tr style=\"height: 15px\">\n<td style=\"width: 234.56px;height: 10px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\"><strong>Skin disorders caused by external agents<\/strong><\/span><\/p>\n<p><span style=\"color: #000000\">Cutaneous adverse reactions can occur because of reactions to drugs or other external agents. Adverse reactions can also occur from heat and cold exposures.<\/span><\/td>\n<td style=\"width: 228.634px;height: 10px;vertical-align: top\">&nbsp;<\/p>\n<p style=\"text-align: left\"><span style=\"color: #000000\">Steven-Johnson syndrome and<br \/>\ntoxic epidermal necrolysis are rare life-threatening skin disorders where the skin peels and blisters often caused by a medications and infections. Toxic erythema from chemotherapy is a skin reaction including eruptions of red\/purple rash and plaques.<br \/>\nPhotosensitivity is a skin sensitivity when exposed to the sun c<\/span><span style=\"color: #000000;font-family: inherit;font-size: inherit\">aused by medications like chemotherapy drugs, HIV medications and antibiotics, frostbite.<\/span><\/p>\n<\/td>\n<td style=\"width: 200px;height: 10px;vertical-align: top\">&nbsp;<\/p>\n<p><span style=\"color: #000000\">Skin reactions like rashes that start after exposure to external agents like medications.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div style=\"text-align: left;\"><\/div>\n<p><span style=\"color: #000000\">*genetic disorders not listed<\/span><\/p>\n<p>&nbsp;<\/p>\n<div class=\"textbox textbox--examples\">\n<header class=\"textbox__header\">\n<h2 class=\"textbox__title\" style=\"text-align: center\"><strong>Clinical Tip<\/strong><\/h2>\n<\/header>\n<div class=\"textbox__content\">\n<p><span style=\"color: #000000\">Did you know that some dermatological conditions are emergencies? For example, necrotizing fasciitis (a rare bacterial infection also known as flesh-eating disease) can spread very quickly throughout the body, at a rate of 1 inch per hour. Symptoms include erythema, warmth to the touch, swelling, severe pain, and fever. If not treated immediately, it can lead to <button class=\"glossary-term\" aria-describedby=\"1090-1384\">sepsis<\/button>, <button class=\"glossary-term\" aria-describedby=\"1090-1386\">shock<\/button>, organ failure, and even death. As a nurse, you must report these findings to the physician or nurse practitioner so immediate treatment can be started.<\/span><\/p>\n<\/div>\n<\/div>\n<div class=\"textbox textbox--exercises\">\n<header class=\"textbox__header\">\n<h2 class=\"textbox__title\" style=\"text-align: center\"><strong>Knowledge Bites: Pathophysiology<\/strong><\/h2>\n<\/header>\n<div class=\"textbox__content\">\n<p><span style=\"color: #000000\">How do you distinguish between common viral and bacterial infections? Common characteristics of a bacterial infection are inflammation, <button class=\"glossary-term\" aria-describedby=\"1090-1382\">exudate <\/button> (such as pus), erythema, swelling, pain, odour. Common characteristics of a viral infection are a grouping\/cluster of lesions, generally asymmetrical (one side of body), and specific regions on the body (e.g., mouth, nose, feet, hands).<\/span><\/p>\n<\/div>\n<\/div>\n<h2><span>Activity: Check Your Understanding<\/span><\/h2>\n<p><span>Name the integument pathophysiology images:<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span><\/p>\n<div id=\"h5p-76\">\n<div class=\"h5p-iframe-wrapper\"><iframe id=\"h5p-iframe-76\" class=\"h5p-iframe\" data-content-id=\"76\" style=\"height:1px\" src=\"about:blank\" frameBorder=\"0\" scrolling=\"no\" title=\"Integumentary - Intro\"><\/iframe><\/div>\n<\/div>\n<p><\/span><\/p>\n<div class=\"glossary\"><div class=\"glossary__tooltip\" id=\"1090-1434\" hidden><p>sometimes referred to as oil glands and produce and secrete sebum (a protective substance that helps retain moisture) all over the body except the palms of hands and the soles of feet.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1436\" hidden><p>is excessive perspiration.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1474\" hidden><p>a discolouration that can appear as a grey\/white shade with people of darker skin tones and a dusky bluish\/purple shade in people with yellow and lighter skin tones, often visualized in the extremities (fingertips, toes, palms of hands, and soles of feet), conjunctiva and circumoral (around lips) and mucous membranes. Often caused by lack of oxygen in the blood and issues with tissue perfusion caused by conditions related to the respiratory, cardiovascular, and peripheral vascular systems.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1476\" hidden><p>is a discolouration that can appear as a grey shade to the mucous membranes\/lips, nail beds, extremities in people with darker skin tones, a yellowish shade in people with lighter brown skin, a pale whitish shade in people with lighter skin tones, and a white or very pale pink conjunctiva in all people. The discolouration reflects a combination of the client\u2019s normal skin colour and the connective tissue (white) with the lack of oxygenated hemoglobin due to many states when the sympathetic nervous system is activated (with stress), hypothermia, shock, and anemia. Pallor affects the integument colour because blood is shunted towards the vital organs.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1432\" hidden><p>are a highly infectious viral infection characterized by a fever and a rash.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1492\" hidden><p>refers to something that is mild, non-invasive and doesn't spread (i.e., non-cancerous)<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1426\" hidden><p>viral infection that can cause a painful rash.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1428\" hidden><p>is an area of the skin that follows a single spinal nerve root.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1414\" hidden><p>is a skin condition that causes a rash, scaling, and itching.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1416\" hidden><p>is a skin condition that causes dry skin and inflammation.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1418\" hidden><p>is a condition that mainly affects the scalp, causing scaly patches and inflammation.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1420\" hidden><p>is a chronic skin condition characterized by patches of depigmented skin.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1422\" hidden><p>is an autoimmune disease that causes inflammation.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1424\" hidden><p>is hair loss.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1412\" hidden><p>to set clear and obvious borders of where the condition starts and ends<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1410\" hidden><p>are red, benign growths on skin made of blood vessels.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1406\" hidden><p>is another term for itchiness.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1408\" hidden><p>is a chronic condition causing itching.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1394\" hidden><p>a term indicating something related to the skin.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1396\" hidden><p>an abnormal growth.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1430\" hidden><p>refers to abnormal cell division (i.e., cancer).<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1398\" hidden><p>is a small patch of skin that is darker than surrounding skin.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1400\" hidden><p>is dark brown pigmented skin\/spot present at birth.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1482\" hidden><p>is a mole.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1402\" hidden><p>is a benign growth associated with aging.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1404\" hidden><p>are encapsulated sacs under the skin filled with material, fluid or gas.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1484\" hidden><p>is a mole with irregular features.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1486\" hidden><p>is a type of skin cancer, commonly found on the face.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1488\" hidden><p>is a type of skin cancer.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1490\" hidden><p>is an aggressive and severe type of skin cancer.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1384\" hidden><p>is a life-threatening bodily response to infection that can lead to tissue damage.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1386\" hidden><p>is a life-threatening state whereby the body is not getting enough blood flow.<\/p>\n<\/div><div class=\"glossary__tooltip\" id=\"1090-1382\" hidden><p>is fluid seeping from a lesion.<\/p>\n<\/div><\/div>","protected":false},"author":34,"menu_order":2,"template":"","meta":{"pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":"cc-by-nc"},"chapter-type":[],"contributor":[85],"license":[56],"class_list":["post-1090","chapter","type-chapter","status-publish","hentry","contributor-january-2023","license-cc-by-nc"],"part":1074,"_links":{"self":[{"href":"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-json\/pressbooks\/v2\/chapters\/1090","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-json\/wp\/v2\/users\/34"}],"version-history":[{"count":4,"href":"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-json\/pressbooks\/v2\/chapters\/1090\/revisions"}],"predecessor-version":[{"id":1878,"href":"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-json\/pressbooks\/v2\/chapters\/1090\/revisions\/1878"}],"part":[{"href":"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-json\/pressbooks\/v2\/parts\/1074"}],"metadata":[{"href":"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-json\/pressbooks\/v2\/chapters\/1090\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-json\/wp\/v2\/media?parent=1090"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-json\/pressbooks\/v2\/chapter-type?post=1090"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-json\/wp\/v2\/contributor?post=1090"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/pressbooks.library.torontomu.ca\/assessmentnursingmain\/wp-json\/wp\/v2\/license?post=1090"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}