{"id":152,"date":"2021-08-14T12:57:36","date_gmt":"2021-08-14T16:57:36","guid":{"rendered":"https:\/\/pressbooks.library.ryerson.ca\/dietmods\/?post_type=chapter&#038;p=152"},"modified":"2025-08-11T11:48:30","modified_gmt":"2025-08-11T15:48:30","slug":"pn-plan","status":"publish","type":"chapter","link":"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/","title":{"raw":"Plan","rendered":"Plan"},"content":{"raw":"<img src=\"http:\/\/pressbooks.library.ryerson.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2022\/02\/label_2-plan-1024x132.png\" alt=\"Step 2: Plan\" width=\"1024\" height=\"132\" class=\"alignnone wp-image-1368 size-large\" \/>\r\n<h1>Team Rounds<\/h1>\r\n<div>Team rounds are an opportunity to collaborate and communicate with the interdisciplinary team. You may update the team about your patient\u2019s care plan and gather important information on their diagnosis, prognosis, consults, current status, expected progression, next steps and disposition planning.<\/div>\r\n<div><\/div>\r\n<div>\r\n\r\n[caption id=\"attachment_1467\" align=\"aligncenter\" width=\"1024\"]<img src=\"http:\/\/pressbooks.library.ryerson.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/lt-jasmyne-avery-assigned-to-naval-hospital-camp-pendleton-performs-rounds-b3ff36.jpg\" alt=\"5 hospital staff including doctors and nurses gather around medical equipment in a hospital. One of the doctors is gesticulating while others listen during rounds.\" width=\"1024\" height=\"678\" class=\"wp-image-1467 size-full\" \/> A doctor, nurse, and other medical staff are pictured conducting rounds in a hospital.<br \/><a href=\"https:\/\/picryl.com\/media\/lt-jasmyne-avery-assigned-to-naval-hospital-camp-pendleton-performs-rounds-b3ff36\">Photo by Madailein Abbott<\/a> is licensed under <a href=\"https:\/\/creativecommons.org\/share-your-work\/public-domain\/pdm\/\">Public Domain<\/a>.[\/caption]\r\n\r\n<\/div>\r\n<div><\/div>\r\n<div>\r\n<div class=\"textbox textbox--exercises\"><header class=\"textbox__header\">\r\n<h2 class=\"textbox__title\">Poppy's PN Plan<\/h2>\r\n<\/header>\r\n<div class=\"textbox__content\">\r\n\r\nWhen a dietitian is asked to assess a patient for PN, the first question should be \u201cIs PN appropriate for this patient?\u201d PN is an invasive, expensive and high-risk treatment compared to other methods of feeding.\r\n\r\nIn making your decision, consider the following about Poppy:\r\n<ul>\r\n \t<li>She is not tolerating EN.<\/li>\r\n \t<li>She is critically ill (catabolic), with an acute kidney injury, and has lost a significant amount of weight preoperatively.<\/li>\r\n \t<li>Her history of severe PVD may contribute to a prolonged period of poor tolerance to enteral nutrition.<\/li>\r\n<\/ul>\r\nThese factors coupled with inadequate nutrition support postoperatively may increase the chance of poor outcomes, morbidity and mortality.\r\n\r\nTherefore, Poppy is appropriate for parenteral nutrition support.\r\n\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<h1>Timing of PN Initiation<\/h1>\r\nInitiation of parenteral nutrition may differ based on clinical indication and severity of malnutrition. It is common practice to initiate PN sooner for patients who are malnourished and are unable to meet their estimated nutrition requirements with oral intake or enteral nutrition.\u00a0 Other factors may also influence initiation of PN. However, general guidelines regarding initiation of PN are listed below.\r\n<ul>\r\n \t<li>For <strong>well-nourished, stable<\/strong> patients: Initiate parenteral nutrition after 5 to 7 days if unable to receive &gt; 50% of estimated requirements orally or enterally.<\/li>\r\n \t<li>Patients who are <strong>nutritionally-at-risk<\/strong> and unlikely to achieve adequate oral or enteral intake: Initiate parenteral nutrition within 3 to 5 days.<\/li>\r\n \t<li>In patients with <strong>baseline<\/strong> moderate or severe malnutrition and insufficient or unattainable oral\u00a0 or enteral intake: Initiate parenteral nutrition as soon as possible.<\/li>\r\n \t<li>For patients with <strong>severe metabolic instability<\/strong>: Delay initiation of parenteral nutrition until their condition has improved.<\/li>\r\n<\/ul>\r\n<h1>Reminder of PN Formulations<\/h1>\r\n<h2>Macronutrients<\/h2>\r\nThe energy that is provided from macronutrients in PN is slightly different than the energy provided in other forms of nutrition (i.e. enteral formulas, food, beverages). Please note the differences below and ensure you use the correct values when determining your PN care plan.\r\n\r\nCaloric contributions of macronutrients:\r\n<ul>\r\n \t<li><strong>Protein<\/strong>: 1 g amino acid = 4.0 kcals<\/li>\r\n \t<li><strong>Carbohydrate<\/strong>: 1 g dextrose = 3.4 kcals<\/li>\r\n \t<li><strong>Lipid<\/strong>: 1 g lipid = 10 kcals<\/li>\r\n<\/ul>\r\n<h2>Lipids<\/h2>\r\nDepending on your hospital formulary, you may have access to various lipid emulsions. These emulsions vary in omega-3, 6 and 9 content. You should seek further readings regarding the use of various lipid emulsions and the associated advantages, disadvantages, and possible situations that they may be used in.\r\n<ul>\r\n \t<li><strong>Intralipid<\/strong>: made of safflower or soybean oil + glycerol emulsifier + phospholipid (egg) and available as 10%, 20% &amp; 30%<\/li>\r\n \t<li><strong>SMOFlipid<\/strong>: soybean oil, medium chain triglycerides (MCT), olive oil, and fish oil (6%\/6%\/5%\/3% w\/v)<\/li>\r\n \t<li><strong>Omegavan<\/strong>: purely fish oils, DHA, EPA<\/li>\r\n \t<li><strong>ClinOleic<\/strong>: olive oil<\/li>\r\n<\/ul>\r\n<table class=\"grid\" style=\"height: 121px\"><caption>Lipid emulsion concentrations<\/caption>\r\n<tbody>\r\n<tr style=\"height: 35px\">\r\n<th style=\"height: 35px;width: 316.91px\" scope=\"col\">Lipid Emulsions<\/th>\r\n<th style=\"height: 35px;width: 129.861px\" scope=\"col\">Omega-3<\/th>\r\n<th style=\"height: 35px;width: 129.861px\" scope=\"col\">Omega-6<\/th>\r\n<th style=\"height: 35px;width: 129.861px\" scope=\"col\">Omega-9<\/th>\r\n<th style=\"height: 35px;width: 137.726px\" scope=\"col\">Saturated<\/th>\r\n<th style=\"height: 35px;width: 76.9618px\" scope=\"col\">MCT<\/th>\r\n<\/tr>\r\n<tr style=\"height: 17px\">\r\n<th style=\"height: 17px;width: 316.91px\" scope=\"row\">Soybean oil emulsion<\/th>\r\n<td style=\"height: 17px;width: 128.438px\">5%<\/td>\r\n<td style=\"height: 17px;width: 128.438px\">60%<\/td>\r\n<td style=\"height: 17px;width: 128.438px\">20%<\/td>\r\n<td style=\"height: 17px;width: 136.302px\">15%<\/td>\r\n<td style=\"height: 17px;width: 75.5382px\">-<\/td>\r\n<\/tr>\r\n<tr style=\"height: 35px\">\r\n<th style=\"height: 35px;width: 316.91px\" scope=\"row\">Olive-soybean oil mixture<\/th>\r\n<td style=\"height: 35px;width: 128.438px\">3%<\/td>\r\n<td style=\"height: 35px;width: 128.438px\">20%<\/td>\r\n<td style=\"height: 35px;width: 128.438px\">60%<\/td>\r\n<td style=\"height: 35px;width: 136.302px\">17%<\/td>\r\n<td style=\"height: 35px;width: 75.5382px\">-<\/td>\r\n<\/tr>\r\n<tr style=\"height: 17px\">\r\n<th style=\"height: 17px;width: 316.91px\" scope=\"row\">Fish oil emulsion<\/th>\r\n<td style=\"height: 17px;width: 128.438px\">60%<\/td>\r\n<td style=\"height: 17px;width: 128.438px\">10%<\/td>\r\n<td style=\"height: 17px;width: 128.438px\">10%<\/td>\r\n<td style=\"height: 17px;width: 136.302px\">20%<\/td>\r\n<td style=\"height: 17px;width: 75.5382px\">-<\/td>\r\n<\/tr>\r\n<tr style=\"height: 17px\">\r\n<th style=\"height: 17px;width: 316.91px\" scope=\"row\">SMOF emulsion<\/th>\r\n<td style=\"height: 17px;width: 128.438px\">10%<\/td>\r\n<td style=\"height: 17px;width: 128.438px\">20%<\/td>\r\n<td style=\"height: 17px;width: 128.438px\">30%<\/td>\r\n<td style=\"height: 17px;width: 136.302px\">10%<\/td>\r\n<td style=\"height: 17px;width: 75.5382px\">30%<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<h2>Micronutrients<\/h2>\r\nVitamins, minerals, and trace elements should be included in parenteral nutrition solutions as depletion of a compromised patient\u2019s micronutrient reserves could impair the patient\u2019s ability to absorb and utilize nutrients.\r\n\r\nElectrolytes are also added to PN solutions. Unlike vitamins, minerals and trace elements, electrolytes must be adjusted daily in a patient who is starting PN to account for losses, disease effects and organ function.\r\n\r\nThere are guidelines which <span style=\"font-size: 1em\">govern how much calcium and phosphorus can be given to avoid precipitates. <\/span><span style=\"font-size: 1em\">Acetate is added to buffer acid from amino acids as bicarbonate cannot be added.\u00a0 Large electrolyte deficiencies must be corrected by IV boluses (ordered by the MD\/NP) prior to initiating PN or advancing solutions.\u00a0 <\/span>Institutional formularies<span style=\"font-size: 1em\"> will determine which micronutrients are available and training should be provided to ensure safe delivery to patients.\u00a0<\/span>\r\n\r\nHere is a sample electrolyte regimen for a stable patient receiving PN:\r\n<ul>\r\n \t<li><strong>Na<\/strong>: 80 - 120 mmol\/day - with chloride, acetate<\/li>\r\n \t<li><strong>K<\/strong>: 40 - 80 mmol\/day - with chloride, phosphate or acetate<\/li>\r\n \t<li><strong>Mg<\/strong>: 10 - 15 mmol\/day - as sulfate salt<\/li>\r\n \t<li><strong>PO<sub>4<\/sub><\/strong>: 8 - 16 mmol\/day - with Na or K<\/li>\r\n<\/ul>\r\n<h1>PN Procurement<\/h1>\r\nPN is compounded in hospital pharmacy. Solutions may be individualized or standardized formulas, depending on the institution.\r\n\r\nThere are t<span style=\"font-size: 1em\">wo types of PN procurement: <\/span>\r\n<ul>\r\n \t<li><span style=\"font-size: 1em\">\u201c3-in-1\u201d AA\/dextrose\/lipid\/electrolytes in one bag<\/span><\/li>\r\n \t<li><span style=\"font-size: 1em\">\u201c2-in-1\u201d AA\/dextrose\/electrolytes + lipid in a separate bag.<\/span><\/li>\r\n<\/ul>\r\n[caption id=\"attachment_1493\" align=\"aligncenter\" width=\"500\"]<img src=\"http:\/\/pressbooks.library.ryerson.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/PN-Procurement-300x300.png\" alt=\"Illustration of a 2-in-1 PN procurement. A double lumen catheter has a y-connector leading to two bags: 1. amino acids, dextrose, electrolytes, vitamins and minerals; 2. Lipid.\" width=\"500\" height=\"502\" class=\"wp-image-1493\" style=\"padding-left: 0px\" \/> Illustration of a 2-in-1 PN procurement. A double lumen catheter has a y-connector leading to two bags: 1. amino acids, dextrose, electrolytes, vitamins and minerals; 2. Lipid.[\/caption]\r\n\r\nSome hospitals have a pre-determined <strong>standardized formulary<\/strong> for ease of ordering and preparing PN. The pre-determined formulas are all named and vary in macronutrient volumes. Additives are individualized based on patients\u2019 needs. The RD chooses the solution which closely matches the patient\u2019s requirements. <em>Here is an example of a standardized bag order form: <a href=\"http:\/\/pressbooks.library.ryerson.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/Sample-PN-Formulary.pdf\">Sample PN Formulary (PDF).<\/a><\/em>\r\n\r\nSome hospitals have <strong>individualized formulas<\/strong> which are prepared for a specific patient. If the hospital has a variety of solutions available, the RD can customize the PN formula to very closely match a patient\u2019s estimated requirements. If there is a limited number of solutions, the PN formula may not be ideal to meet each estimated requirement.\r\n\r\nIt is possible that some <span style=\"font-size: 1em\">hospitals may have both standardized and individualized formularies. If a standardized formula is not appropriate, the RD would calculate a custom solution.<\/span>\r\n<h1>PN Administration<\/h1>\r\nWhen a patient is started on PN, it g<span style=\"font-size: 1em\">enerally takes about 2 - 4 days to achieve goal volumes while monitoring metabolic tolerance.\u00a0 <\/span><span style=\"font-size: 1em\">However, this may differ for specific patients:<\/span>\r\n<ul>\r\n \t<li>Patients who are very malnourished or show signs and symptoms of refeeding syndrome may take up to 7 days to safely receive goal volumes. <span style=\"font-size: 1em\">Electrolytes, fluid and dextrose may need several steps of adjustment before a patient receives their goal <\/span><span style=\"text-align: initial;font-size: 1em\">nutrition<\/span><span style=\"font-size: 1em\"> provision.<\/span><\/li>\r\n \t<li>For patients who have diabetes or elevated blood glucose levels, it may take several days to adjust the patient's insulin regime for acceptable glycemic control.<\/li>\r\n<\/ul>\r\nIt is common for r<span style=\"text-align: initial;font-size: 1em\">outine bloodwork to be drawn to monitor metabolic tolerance pre-PN and day 1, 2, 3 after starting PN. Typically after a patient has been stable on their goal volume of PN, bloodwork is drawn once or twice a week according to the institution's protocol (unless the patient\u2019s medical condition requires a different monitoring schedule). <\/span>\r\n\r\n<span style=\"text-align: initial;font-size: 1em\">When starting PN, it is<\/span><span style=\"font-size: 1em\"> usually given over 24 hours. <\/span><span style=\"font-size: 1em\">Patients who require long-term PN have their delivery cycled to fewer hours to provide freedom from the IV pump\/pole and improve quality of life (QOL). PN would be given over 20 hours a day, followed by 16 hours a day, followed by 12 hours a day.\u00a0<\/span>\r\n\r\n&nbsp;\r\n<div class=\"textbox textbox--exercises\"><header class=\"textbox__header\">\r\n<h2 class=\"textbox__title\">Poppy's Parenteral Regime: Formula Selection<\/h2>\r\n<\/header>\r\n<div class=\"textbox__content\">\r\n<div class=\"textbox\">\r\n\r\n<strong>Take note of Poppy\u2019s estimated requirements:<\/strong>\r\n<ul>\r\n \t<li>Weight: 63 kg<\/li>\r\n \t<li>Energy:\u00a0 1575-1890 kcals\/day<\/li>\r\n \t<li>Protein: 76-95 g\/day<\/li>\r\n \t<li>Fluid: very conservative<\/li>\r\n<\/ul>\r\n<\/div>\r\nThe first step in determining Poppy\u2019s parenteral plan is to select a solution. As mentioned, depending on your hospital, you will have access to different amino acid, dextrose and lipid solutions. In this case, we have access to a 5% amino acid solution, and varying dextrose solutions of 10%, 16.6%, and 25%. You can determine the energy content of each TPN solution by calculating the gram amount of amino acid and dextrose in 1L of solution. Depending on your patients needs, you can select a less or more concentrated solution.\r\n<div class=\"textbox\">\r\n\r\n<strong>Pause and consider which of the solutions you would choose, based on Poppy\u2019s requirements<\/strong>:\r\n<ol>\r\n \t<li style=\"list-style-type: upper-alpha\">5% amino acid (aa) + <strong>10% dextrose<\/strong> (dex)\r\n<ul>\r\n \t<li>50 g aa \u00d7 4 kcal\/g = 200 kcal<\/li>\r\n \t<li>100 g dex \u00d7 3.4 kcal\/g = 340 kcal<\/li>\r\n \t<li>1 L TPN = 540 kcal<\/li>\r\n<\/ul>\r\n<\/li>\r\n \t<li style=\"list-style-type: upper-alpha\">5% amino acid + <strong>16.6% dextrose<\/strong>\r\n<ul>\r\n \t<li>50 g aa \u00d7 4 kcal\/g = 200 kcal<\/li>\r\n \t<li>166 g dex \u00d7 3.4 kcal\/g = 564 kcal<\/li>\r\n \t<li>1 L TPN = 764 kcal<\/li>\r\n<\/ul>\r\n<\/li>\r\n \t<li style=\"list-style-type: upper-alpha\">5% amino acid + <strong>25% dextrose<\/strong>\r\n<ul>\r\n \t<li>50 g aa \u00d7 4 kcal\/g = 200 kcal<\/li>\r\n \t<li>250 g dex \u00d7 3.4 kcal\/g =\u00a0 850 kcal<\/li>\r\n \t<li>1 L TPN = 1050 kcal<\/li>\r\n<\/ul>\r\n<\/li>\r\n<\/ol>\r\n<\/div>\r\nWhen starting\u00a0 to work through your patient's parenteral nutrition plan, it is common to start with calculating protein requirements. Clinicians use various methods to calculate a PN regime, however protein requirements are often a key factor and it is important to meet the patients needs. Therefore, it is suggested that you start by determining a solution that meets Poppy's estimated protein requirements to avoid redoing\u00a0 your calculations multiple times.\r\n\r\n<strong>Protein calculations<\/strong>\r\n<ul>\r\n \t<li>76 g needed \u00f7 50 g (in 1 L) = <strong>need 1.52 bags<\/strong> = 1.52 L<\/li>\r\n \t<li>1.52 L = 50 g aa \u00d7 1.52 = 76 g pro \u00d7 4 kcal\/g = 304 kcal<\/li>\r\n<\/ul>\r\n<p style=\"padding-left: 40px\">If Poppy requires a minimum of 76 g of protein per day, this would require 1.52 L of TPN using a 5% amino acid solution. <em>Protein will contribute 304 calories.<\/em><\/p>\r\n<strong>Carbohydrate calculations<\/strong>\r\n<ul>\r\n \t<li>100 g dex \u00d7 1.52 = 152 g CHO \u00d7 3.4 kcal\/g = 517 kcal<\/li>\r\n \t<li><strong>166 g dex \u00d7 1.52 = 252 g CHO \u00d7 3.4 kcal\/g = 859 kcal<\/strong><\/li>\r\n \t<li>250 g dex \u00d7 1.52 = 380 g CHO \u00d7 3.4 kcal\/g = 1292 kcal<\/li>\r\n<\/ul>\r\n<p style=\"padding-left: 40px\">Based on Poppy's needs, it is reasonable to choose the 16.6% dextrose solution.<strong>\r\n<\/strong><em>This dextrose solution will contribute 859 calories in 1.52 L of the solution<\/em>.<\/p>\r\n<strong style=\"text-align: initial;font-size: 1em\">Lipid calculations<\/strong>\r\n<ul>\r\n \t<li><span style=\"font-size: 1em\">Determine calories from lipid: 1700 kcal\/day = 1700 \u2212 (304 from protein + 859 from CHO) = <\/span><strong style=\"font-size: 1em\">537 kcal needed from 20% lipid<\/strong><\/li>\r\n \t<li>Determine mL of lipid: 537 kcal\/2 kcal\/mL (20%) = 269 mL 20% lipid<\/li>\r\n \t<li>Determine grams of lipid: 537 kcal\/10 kcal\/g = 54 g lipid<\/li>\r\n<\/ul>\r\n<p style=\"padding-left: 40px\">In this case, we want to have a greater caloric contribution from lipid because Poppy\u2019s fluid requirements are restricted. Including a higher amount of lipid results in a more fluid restricted solution as lipids are calorically dense.\r\n<em style=\"text-align: initial;font-size: 1em\">Poppy will receive 537 calories from lipid to meet her needs of approximately 1700 calories a day from TPN.<\/em><\/p>\r\n<span style=\"text-align: initial;font-size: 1em\">Practice these calculations and review the answers.<\/span>\r\n\r\n<\/div>\r\n<\/div>\r\n<div>\r\n<div class=\"textbox textbox--exercises\"><header class=\"textbox__header\">\r\n<h2 class=\"textbox__title\">Poppy's Parenteral Regime: Summary of Formula Selection<\/h2>\r\n<\/header>\r\n<div class=\"textbox__content\">\r\n\r\nHere is a summary of the formula based on 5% amino acid, 16.6% dextrose, 20% SMOFlipid and standard electrolytes.\r\n\r\n<strong>The total amount of fluid is 1789 mL to meet Poppy\u2019s energy needs of 1700 calories a day. <\/strong>\r\n\r\nKeep in mind that you would have need to liaise with the physicians on your team to approve the fluid volume of your TPN order as they have requested that you minimize Poppy's fluid intake.\r\n<div class=\"textbox\">\r\n\r\n5% amino acid \/ 16.6% dextrose + 20% SMOFlipid + standard electrolytes + MVI\r\n<ul>\r\n \t<li>1.52 L 5% amino acid \/ 16.6% dextrose\r\n<ul>\r\n \t<li>76 g pro \/ 304 kcal<\/li>\r\n \t<li>252 g CHO \/ 859 kcal<\/li>\r\n<\/ul>\r\n<\/li>\r\n \t<li>269 mL 20% SMOFlipid\r\n<ul>\r\n \t<li>54 g fat \/ 537 kcal<\/li>\r\n<\/ul>\r\n<\/li>\r\n<\/ul>\r\n<strong>Total<\/strong>: 1789 mL (1520 mL dextrose and AA + 269 mL lipid) \/ 1700 kcal\r\n\r\n<\/div>\r\n&nbsp;\r\n\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<h1>Macronutrient Tolerance and Distribution<\/h1>\r\n<div>After creating your PN regime, it is important to make sure your plan aligns with the guidelines for macronutrient tolerance and distribution. Pause and try calculating the macronutrient tolerance and distribution of your selected formula before moving on.<\/div>\r\n<div>\r\n<table class=\"grid\" style=\"border-collapse: collapse;width: 100%;height: 126px\" border=\"0\"><caption>Macronutrient tolerance and distribution<\/caption>\r\n<tbody>\r\n<tr style=\"height: 17px\">\r\n<td style=\"width: 0.993049%;height: 17px\"><\/td>\r\n<th style=\"width: 30.5661%;height: 17px\" scope=\"col\">Macronutrient tolerance<\/th>\r\n<th style=\"width: 28.4409%;height: 17px\" scope=\"col\">Macronutrient distribution<\/th>\r\n<\/tr>\r\n<tr style=\"height: 19px\">\r\n<th style=\"width: 0.993049%;height: 19px\" scope=\"row\">Dextrose<\/th>\r\n<td style=\"width: 30.5661%;height: 19px\">&lt; 4-5 mg\/kg\/min<\/td>\r\n<td style=\"width: 28.4409%;height: 19px\">45 - 65%<\/td>\r\n<\/tr>\r\n<tr style=\"height: 54px\">\r\n<th style=\"width: 0.993049%;height: 54px\" scope=\"row\">Lipid<\/th>\r\n<td style=\"width: 30.5661%;height: 54px\">\u2264 2.0-2.5 g\/kg\/day (&lt;1.5 g\/kg\/day preferred) or &lt; 30% of daily kcal<\/td>\r\n<td style=\"width: 28.4409%;height: 54px\">10 - 35%<\/td>\r\n<\/tr>\r\n<tr style=\"height: 36px\">\r\n<th style=\"width: 0.993049%;height: 36px\" scope=\"row\">Protein<\/th>\r\n<td style=\"width: 30.5661%;height: 36px\">As per estimated requirements<\/td>\r\n<td style=\"width: 28.4409%;height: 36px\">10 - 35%<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n<div>\r\n<div class=\"textbox textbox--exercises\"><header class=\"textbox__header\">\r\n<h2 class=\"textbox__title\">Poppy\u2019s Parenteral Regime: Macronutrients<\/h2>\r\n<\/header>\r\n<div class=\"textbox__content\">\r\n<div class=\"textbox\">\r\n\r\n<strong>Poppy\u2019s Estimated Requirements<\/strong>\r\n<ul>\r\n \t<li>Weight: 63 kg<\/li>\r\n \t<li>Energy:\u00a0 1575-1890 kcal\/day<\/li>\r\n \t<li>Protein: 76-95 g\/day<\/li>\r\n \t<li>Fluid: very conservative<\/li>\r\n<\/ul>\r\n<\/div>\r\n<div><strong>Macronutrient tolerance<\/strong><\/div>\r\n<ul>\r\n \t<li>Protein as per estimated requirements: 76 g\/63 kg = 1.2 g\/kg<\/li>\r\n \t<li>Lipid \u2264 2.0-2.5 g\/kg\/day: 54 g fat\/63 kg = 0.86 g\/kg<\/li>\r\n \t<li>Dextrose \u2264 4-5 mg\/kg\/min:\r\n<ul>\r\n \t<li>252 g dextrose = 252000 mg<\/li>\r\n \t<li>252000 mg\/63 kg\/1440 min = 2.8 mg\/kg\/min<\/li>\r\n<\/ul>\r\n<\/li>\r\n<\/ul>\r\n<div>\r\n\r\nFor macronutrient tolerance, protein is 1.2 g\/kg which is appropriate on initiation but may need to be adjusted depending on Poppy\u2019s clinical status. Poppy would be receiving 0.86 g\/kg of lipid, and 2.8 mg\/kg\/min of dextrose which is within the guidelines for macronutrient tolerance. In this case, the formula remains appropriate for Poppy.\r\n\r\n<strong>Macronutrient distribution<\/strong>\r\n<ul>\r\n \t<li>Protein = 304 kcal \u00f7 1700 kcal \u00d7 100 = 18%<\/li>\r\n \t<li>Carbohydrate = 859 kcal \u00f7 1700 kcal \u00d7 100 = 51%<\/li>\r\n \t<li>Fat = 537 kcal \u00f7 1700 kcal \u00d7 100 = 32%<\/li>\r\n<\/ul>\r\nThe macronutrient distribution of Poppy's PN solution is 18% protein, 51% carbohydrate, and 32% fat \u2014 all are within the recommended ranges.\u00a0 The amount of protein Poppy will be receiving is on the lower end of the range and the amount of fat she will be receiving is on the higher end of the range. This is acceptable as a limited number of PN solutions are available on our formulary and we are working to meet Poppy's estimated protein requirements and limit total fluid volume. As fat is calorically dense we elected to increase her proportion of fat intake to reduce fluid intake. As with any nutrition care plan , Poppy's estimated nutrition requirements will be re-evaluated periodically based on her clinical status and her PN solution may change.\r\n\r\n<strong>Rate of Administration<\/strong>\r\n<ul>\r\n \t<li>5% amino acid + 16.6% dextrose: 1.52 L = 1520 mL \u00f7 24 hrs = 63 mL\/hour<\/li>\r\n \t<li>20% lipid: 269 mL \u00f7 12 hours = 22 mL\/hour<\/li>\r\n \t<li>TFI: 1520 + 269 mL = 1789 mL\/day (28mL\/kg)<\/li>\r\n<\/ul>\r\nThe last step when planning a parenteral nutrition regime is to calculate the rate of administration. Poppy will receive her \"2 in 1\" solution of amino acids and dextrose (plus additives) at 63 mL\/hour and lipids at 11 mL\/hour. This results in 1789 mL\/day of fluid, which is 28 mL\/kg. The ICU <span class=\"ILfuVd\"><span class=\"hgKElc\">intensivist<\/span><\/span> has approved this fluid volume.\r\n\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<h1>Initiating PN &amp; Refeeding Syndrome<\/h1>\r\n<div>\r\n\r\nWhen your patient is at risk of refeeding syndrome, you should:\r\n<ul>\r\n \t<li>Initiate feeding as soon as possible<\/li>\r\n \t<li>Determine caloric and protein requirements using current weight<\/li>\r\n \t<li>Start nutrition slowly via<span>\u00a0<\/span><strong>continuous infusion<\/strong><\/li>\r\n<\/ul>\r\n<\/div>\r\n<ul>\r\n \t<li><strong>Energy:<\/strong><span>\u00a0<\/span>no more than 50% of energy requirements in the first 24 hours, maximum 15-20 kcal\/kg (if at severe risk: \u226410 kcal\/kg).<\/li>\r\n \t<li><strong>Carbohydrate:<\/strong><span>\u00a0<\/span>&lt;150 g\/day or &lt; 2 mg\/kg\/minute.\u00a0Consider<span>\u00a0<\/span>all sources<span>\u00a0<\/span>of carbohydrates (dextrose containing IV fluids, oral intake, medications).<\/li>\r\n \t<li><strong>Protein:<\/strong><span>\u00a0<\/span>start at the goal of requirements up to 1.5 g\/kg.<\/li>\r\n \t<li><strong>Supplementation:<\/strong><span>\u00a0<\/span>daily multivitamin and 100 mg thiamine \u00d7 3 days.<\/li>\r\n \t<li><strong>Obtain bloodwork:<\/strong><span>\u00a0<\/span>replace low electrolyte levels (prior to initiating feeding, 4-6 hours after initiating feeding, and daily for minimum 5 days).<\/li>\r\n<\/ul>\r\n<\/div>\r\n<div>\r\n<div class=\"textbox textbox--exercises\"><header class=\"textbox__header\">\r\n<h2 class=\"textbox__title\">Poppy's Parenteral Regime: Refeeding Syndrome<\/h2>\r\n<\/header>\r\n<div class=\"textbox__content\">\r\n\r\nAs per our assessment, Poppy is at low-moderate risk of refeeding syndrome.\r\n\r\nDespite the refeeding risk, PN is initiated conservatively to assess metabolic tolerance. The conservative start typically meets the requirements for safely starting nutrition support when a patient is at risk of refeeding syndrome.\r\n\r\nRequest thiamine and multivitamin supplementation for patients who are at risk.\r\n\r\n<\/div>\r\n<\/div>\r\n<h1>Summary of Nutrition Plan<\/h1>\r\n<div class=\"textbox textbox--exercises\"><header class=\"textbox__header\">\r\n<h2 class=\"textbox__title\">Summary of Poppy\u2019s Nutrition Care Plan<\/h2>\r\n<\/header>\r\n<div class=\"textbox__content\">\r\n<table class=\"grid\" style=\"height: 289px\"><caption><span>Summary of recommendations for Poppy\u2019s nutrition care plan<\/span><\/caption>\r\n<tbody>\r\n<tr style=\"height: 17px\">\r\n<th style=\"height: 17px;width: 109.328px\" scope=\"col\">Area of Concern<\/th>\r\n<th style=\"height: 17px;width: 558.062px\" scope=\"col\">Recommendations<\/th>\r\n<\/tr>\r\n<tr style=\"height: 119px\">\r\n<td style=\"height: 119px;width: 109.328125px\">Parenteral Nutrition<\/td>\r\n<td style=\"height: 119px;width: 558.0625px\">\r\n<ul>\r\n \t<li>5% amino acid + 16.6% dextrose: 1.52 L = 63 mL\/hour x 24 hours (PRO 18%, CHO 51%)<\/li>\r\n \t<li>20% lipid: 269 mL= 22 mL\/hour x 12 hours (FAT 32%)<\/li>\r\n \t<li>TFI: 1520 + 269 mL = 1789 mL\/day (28 mL\/kg)- volume approved by MD<\/li>\r\n \t<li>Initiate slowly at ~ 50% of poppy's requirements<\/li>\r\n \t<li>Monitor closely for refeeding and PN complications \u2013 see implementation section<\/li>\r\n<\/ul>\r\n<\/td>\r\n<\/tr>\r\n<tr style=\"height: 51px\">\r\n<td style=\"height: 51px;width: 109.328125px\">Medications and Infusions<\/td>\r\n<td style=\"height: 51px;width: 558.0625px\">\r\n<ul>\r\n \t<li>NS @ 10 mL\/hour = 240 mL\/day<\/li>\r\n \t<li>Ongoing diuresis (furosemide): monitor fluid balance and urine output for fluid overload; adjust nutrition care plan if indicated<\/li>\r\n<\/ul>\r\n<\/td>\r\n<\/tr>\r\n<tr style=\"height: 34px\">\r\n<td style=\"height: 34px;width: 109.328125px\">Laboratory Values<\/td>\r\n<td style=\"height: 34px;width: 558.0625px\">\r\n<ul>\r\n \t<li>Monitor electrolytes and hemodynamic stability daily<\/li>\r\n \t<li>Sodium slightly low (132) \u2013 monitor<\/li>\r\n<\/ul>\r\n<\/td>\r\n<\/tr>\r\n<tr style=\"height: 51px\">\r\n<td style=\"height: 51px;width: 109.328125px\">Supplements<\/td>\r\n<td style=\"height: 51px;width: 558.0625px\">\r\n<ul>\r\n \t<li>Add a daily multivitamin for risk of refeeding syndrome<\/li>\r\n \t<li>Add 100 mg thiamine \u00d7 3 days when initiating PN due to risk of refeeding syndrome<\/li>\r\n<\/ul>\r\n<\/td>\r\n<\/tr>\r\n<tr style=\"height: 17px\">\r\n<td style=\"height: 17px;width: 109.328125px\">Diet<\/td>\r\n<td style=\"height: 17px;width: 558.0625px\">\r\n<ul>\r\n \t<li>NPO \u2013 re: doctors orders and intolerance to EN<\/li>\r\n<\/ul>\r\n<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n<\/div>\r\n<h1>Simulation Activity: Poppy<\/h1>\r\n[h5p id=\"64\"]\r\n<div class=\"textbox shaded\">\r\n\r\nPART 2: PLAN COMPLETE. Pause to reflect on the nutrition care plan we created for Poppy. When you\u2019re ready, move on to Part 3: Implementation.\r\n\r\n<\/div>\r\n&nbsp;\r\n\r\n<\/div>\r\n<div><\/div>","rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_80 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Page Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-69d58640f10e8\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-69d58640f10e8\" checked aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#Team_Rounds\" >Team Rounds<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#Poppys_PN_Plan\" >Poppy&#8217;s PN Plan<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#Timing_of_PN_Initiation\" >Timing of PN Initiation<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#Reminder_of_PN_Formulations\" >Reminder of PN Formulations<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#Macronutrients\" >Macronutrients<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#Lipids\" >Lipids<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#Micronutrients\" >Micronutrients<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#PN_Procurement\" >PN Procurement<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#PN_Administration\" >PN Administration<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#Poppys_Parenteral_Regime_Formula_Selection\" >Poppy&#8217;s Parenteral Regime: Formula Selection<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#Poppys_Parenteral_Regime_Summary_of_Formula_Selection\" >Poppy&#8217;s Parenteral Regime: Summary of Formula Selection<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#Macronutrient_Tolerance_and_Distribution\" >Macronutrient Tolerance and Distribution<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#Poppys_Parenteral_Regime_Macronutrients\" >Poppy\u2019s Parenteral Regime: Macronutrients<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#Initiating_PN_Refeeding_Syndrome\" >Initiating PN &amp; Refeeding Syndrome<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#Poppys_Parenteral_Regime_Refeeding_Syndrome\" >Poppy&#8217;s Parenteral Regime: Refeeding Syndrome<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#Summary_of_Nutrition_Plan\" >Summary of Nutrition Plan<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#Summary_of_Poppys_Nutrition_Care_Plan\" >Summary of Poppy\u2019s Nutrition Care Plan<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/chapter\/pn-plan\/#Simulation_Activity_Poppy\" >Simulation Activity: Poppy<\/a><\/li><\/ul><\/nav><\/div>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/pressbooks.library.ryerson.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2022\/02\/label_2-plan-1024x132.png\" alt=\"Step 2: Plan\" width=\"1024\" height=\"132\" class=\"alignnone wp-image-1368 size-large\" srcset=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2022\/02\/label_2-plan-1024x132.png 1024w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2022\/02\/label_2-plan-300x39.png 300w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2022\/02\/label_2-plan-768x99.png 768w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2022\/02\/label_2-plan-1536x198.png 1536w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2022\/02\/label_2-plan-2048x264.png 2048w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2022\/02\/label_2-plan-65x8.png 65w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2022\/02\/label_2-plan-225x29.png 225w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2022\/02\/label_2-plan-350x45.png 350w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/p>\n<h1><span class=\"ez-toc-section\" id=\"Team_Rounds\"><\/span>Team Rounds<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<div>Team rounds are an opportunity to collaborate and communicate with the interdisciplinary team. You may update the team about your patient\u2019s care plan and gather important information on their diagnosis, prognosis, consults, current status, expected progression, next steps and disposition planning.<\/div>\n<div><\/div>\n<div>\n<figure id=\"attachment_1467\" aria-describedby=\"caption-attachment-1467\" style=\"width: 1024px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/pressbooks.library.ryerson.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/lt-jasmyne-avery-assigned-to-naval-hospital-camp-pendleton-performs-rounds-b3ff36.jpg\" alt=\"5 hospital staff including doctors and nurses gather around medical equipment in a hospital. One of the doctors is gesticulating while others listen during rounds.\" width=\"1024\" height=\"678\" class=\"wp-image-1467 size-full\" srcset=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/lt-jasmyne-avery-assigned-to-naval-hospital-camp-pendleton-performs-rounds-b3ff36.jpg 1024w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/lt-jasmyne-avery-assigned-to-naval-hospital-camp-pendleton-performs-rounds-b3ff36-300x199.jpg 300w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/lt-jasmyne-avery-assigned-to-naval-hospital-camp-pendleton-performs-rounds-b3ff36-768x509.jpg 768w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/lt-jasmyne-avery-assigned-to-naval-hospital-camp-pendleton-performs-rounds-b3ff36-65x43.jpg 65w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/lt-jasmyne-avery-assigned-to-naval-hospital-camp-pendleton-performs-rounds-b3ff36-225x149.jpg 225w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/lt-jasmyne-avery-assigned-to-naval-hospital-camp-pendleton-performs-rounds-b3ff36-350x232.jpg 350w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption id=\"caption-attachment-1467\" class=\"wp-caption-text\">A doctor, nurse, and other medical staff are pictured conducting rounds in a hospital.<br \/><a href=\"https:\/\/picryl.com\/media\/lt-jasmyne-avery-assigned-to-naval-hospital-camp-pendleton-performs-rounds-b3ff36\">Photo by Madailein Abbott<\/a> is licensed under <a href=\"https:\/\/creativecommons.org\/share-your-work\/public-domain\/pdm\/\">Public Domain<\/a>.<\/figcaption><\/figure>\n<\/div>\n<div><\/div>\n<div>\n<div class=\"textbox textbox--exercises\">\n<header class=\"textbox__header\">\n<h2 class=\"textbox__title\"><span class=\"ez-toc-section\" id=\"Poppys_PN_Plan\"><\/span>Poppy&#8217;s PN Plan<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<\/header>\n<div class=\"textbox__content\">\n<p>When a dietitian is asked to assess a patient for PN, the first question should be \u201cIs PN appropriate for this patient?\u201d PN is an invasive, expensive and high-risk treatment compared to other methods of feeding.<\/p>\n<p>In making your decision, consider the following about Poppy:<\/p>\n<ul>\n<li>She is not tolerating EN.<\/li>\n<li>She is critically ill (catabolic), with an acute kidney injury, and has lost a significant amount of weight preoperatively.<\/li>\n<li>Her history of severe PVD may contribute to a prolonged period of poor tolerance to enteral nutrition.<\/li>\n<\/ul>\n<p>These factors coupled with inadequate nutrition support postoperatively may increase the chance of poor outcomes, morbidity and mortality.<\/p>\n<p>Therefore, Poppy is appropriate for parenteral nutrition support.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<h1><span class=\"ez-toc-section\" id=\"Timing_of_PN_Initiation\"><\/span>Timing of PN Initiation<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p>Initiation of parenteral nutrition may differ based on clinical indication and severity of malnutrition. It is common practice to initiate PN sooner for patients who are malnourished and are unable to meet their estimated nutrition requirements with oral intake or enteral nutrition.\u00a0 Other factors may also influence initiation of PN. However, general guidelines regarding initiation of PN are listed below.<\/p>\n<ul>\n<li>For <strong>well-nourished, stable<\/strong> patients: Initiate parenteral nutrition after 5 to 7 days if unable to receive &gt; 50% of estimated requirements orally or enterally.<\/li>\n<li>Patients who are <strong>nutritionally-at-risk<\/strong> and unlikely to achieve adequate oral or enteral intake: Initiate parenteral nutrition within 3 to 5 days.<\/li>\n<li>In patients with <strong>baseline<\/strong> moderate or severe malnutrition and insufficient or unattainable oral\u00a0 or enteral intake: Initiate parenteral nutrition as soon as possible.<\/li>\n<li>For patients with <strong>severe metabolic instability<\/strong>: Delay initiation of parenteral nutrition until their condition has improved.<\/li>\n<\/ul>\n<h1><span class=\"ez-toc-section\" id=\"Reminder_of_PN_Formulations\"><\/span>Reminder of PN Formulations<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<h2><span class=\"ez-toc-section\" id=\"Macronutrients\"><\/span>Macronutrients<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The energy that is provided from macronutrients in PN is slightly different than the energy provided in other forms of nutrition (i.e. enteral formulas, food, beverages). Please note the differences below and ensure you use the correct values when determining your PN care plan.<\/p>\n<p>Caloric contributions of macronutrients:<\/p>\n<ul>\n<li><strong>Protein<\/strong>: 1 g amino acid = 4.0 kcals<\/li>\n<li><strong>Carbohydrate<\/strong>: 1 g dextrose = 3.4 kcals<\/li>\n<li><strong>Lipid<\/strong>: 1 g lipid = 10 kcals<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"Lipids\"><\/span>Lipids<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Depending on your hospital formulary, you may have access to various lipid emulsions. These emulsions vary in omega-3, 6 and 9 content. You should seek further readings regarding the use of various lipid emulsions and the associated advantages, disadvantages, and possible situations that they may be used in.<\/p>\n<ul>\n<li><strong>Intralipid<\/strong>: made of safflower or soybean oil + glycerol emulsifier + phospholipid (egg) and available as 10%, 20% &amp; 30%<\/li>\n<li><strong>SMOFlipid<\/strong>: soybean oil, medium chain triglycerides (MCT), olive oil, and fish oil (6%\/6%\/5%\/3% w\/v)<\/li>\n<li><strong>Omegavan<\/strong>: purely fish oils, DHA, EPA<\/li>\n<li><strong>ClinOleic<\/strong>: olive oil<\/li>\n<\/ul>\n<table class=\"grid\" style=\"height: 121px\">\n<caption>Lipid emulsion concentrations<\/caption>\n<tbody>\n<tr style=\"height: 35px\">\n<th style=\"height: 35px;width: 316.91px\" scope=\"col\">Lipid Emulsions<\/th>\n<th style=\"height: 35px;width: 129.861px\" scope=\"col\">Omega-3<\/th>\n<th style=\"height: 35px;width: 129.861px\" scope=\"col\">Omega-6<\/th>\n<th style=\"height: 35px;width: 129.861px\" scope=\"col\">Omega-9<\/th>\n<th style=\"height: 35px;width: 137.726px\" scope=\"col\">Saturated<\/th>\n<th style=\"height: 35px;width: 76.9618px\" scope=\"col\">MCT<\/th>\n<\/tr>\n<tr style=\"height: 17px\">\n<th style=\"height: 17px;width: 316.91px\" scope=\"row\">Soybean oil emulsion<\/th>\n<td style=\"height: 17px;width: 128.438px\">5%<\/td>\n<td style=\"height: 17px;width: 128.438px\">60%<\/td>\n<td style=\"height: 17px;width: 128.438px\">20%<\/td>\n<td style=\"height: 17px;width: 136.302px\">15%<\/td>\n<td style=\"height: 17px;width: 75.5382px\">&#8211;<\/td>\n<\/tr>\n<tr style=\"height: 35px\">\n<th style=\"height: 35px;width: 316.91px\" scope=\"row\">Olive-soybean oil mixture<\/th>\n<td style=\"height: 35px;width: 128.438px\">3%<\/td>\n<td style=\"height: 35px;width: 128.438px\">20%<\/td>\n<td style=\"height: 35px;width: 128.438px\">60%<\/td>\n<td style=\"height: 35px;width: 136.302px\">17%<\/td>\n<td style=\"height: 35px;width: 75.5382px\">&#8211;<\/td>\n<\/tr>\n<tr style=\"height: 17px\">\n<th style=\"height: 17px;width: 316.91px\" scope=\"row\">Fish oil emulsion<\/th>\n<td style=\"height: 17px;width: 128.438px\">60%<\/td>\n<td style=\"height: 17px;width: 128.438px\">10%<\/td>\n<td style=\"height: 17px;width: 128.438px\">10%<\/td>\n<td style=\"height: 17px;width: 136.302px\">20%<\/td>\n<td style=\"height: 17px;width: 75.5382px\">&#8211;<\/td>\n<\/tr>\n<tr style=\"height: 17px\">\n<th style=\"height: 17px;width: 316.91px\" scope=\"row\">SMOF emulsion<\/th>\n<td style=\"height: 17px;width: 128.438px\">10%<\/td>\n<td style=\"height: 17px;width: 128.438px\">20%<\/td>\n<td style=\"height: 17px;width: 128.438px\">30%<\/td>\n<td style=\"height: 17px;width: 136.302px\">10%<\/td>\n<td style=\"height: 17px;width: 75.5382px\">30%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span class=\"ez-toc-section\" id=\"Micronutrients\"><\/span>Micronutrients<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Vitamins, minerals, and trace elements should be included in parenteral nutrition solutions as depletion of a compromised patient\u2019s micronutrient reserves could impair the patient\u2019s ability to absorb and utilize nutrients.<\/p>\n<p>Electrolytes are also added to PN solutions. Unlike vitamins, minerals and trace elements, electrolytes must be adjusted daily in a patient who is starting PN to account for losses, disease effects and organ function.<\/p>\n<p>There are guidelines which <span style=\"font-size: 1em\">govern how much calcium and phosphorus can be given to avoid precipitates. <\/span><span style=\"font-size: 1em\">Acetate is added to buffer acid from amino acids as bicarbonate cannot be added.\u00a0 Large electrolyte deficiencies must be corrected by IV boluses (ordered by the MD\/NP) prior to initiating PN or advancing solutions.\u00a0 <\/span>Institutional formularies<span style=\"font-size: 1em\"> will determine which micronutrients are available and training should be provided to ensure safe delivery to patients.\u00a0<\/span><\/p>\n<p>Here is a sample electrolyte regimen for a stable patient receiving PN:<\/p>\n<ul>\n<li><strong>Na<\/strong>: 80 &#8211; 120 mmol\/day &#8211; with chloride, acetate<\/li>\n<li><strong>K<\/strong>: 40 &#8211; 80 mmol\/day &#8211; with chloride, phosphate or acetate<\/li>\n<li><strong>Mg<\/strong>: 10 &#8211; 15 mmol\/day &#8211; as sulfate salt<\/li>\n<li><strong>PO<sub>4<\/sub><\/strong>: 8 &#8211; 16 mmol\/day &#8211; with Na or K<\/li>\n<\/ul>\n<h1><span class=\"ez-toc-section\" id=\"PN_Procurement\"><\/span>PN Procurement<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p>PN is compounded in hospital pharmacy. Solutions may be individualized or standardized formulas, depending on the institution.<\/p>\n<p>There are t<span style=\"font-size: 1em\">wo types of PN procurement: <\/span><\/p>\n<ul>\n<li><span style=\"font-size: 1em\">\u201c3-in-1\u201d AA\/dextrose\/lipid\/electrolytes in one bag<\/span><\/li>\n<li><span style=\"font-size: 1em\">\u201c2-in-1\u201d AA\/dextrose\/electrolytes + lipid in a separate bag.<\/span><\/li>\n<\/ul>\n<figure id=\"attachment_1493\" aria-describedby=\"caption-attachment-1493\" style=\"width: 500px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/pressbooks.library.ryerson.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/PN-Procurement-300x300.png\" alt=\"Illustration of a 2-in-1 PN procurement. A double lumen catheter has a y-connector leading to two bags: 1. amino acids, dextrose, electrolytes, vitamins and minerals; 2. Lipid.\" width=\"500\" height=\"502\" class=\"wp-image-1493\" style=\"padding-left: 0px\" srcset=\"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/PN-Procurement-300x300.png 300w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/PN-Procurement-150x150.png 150w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/PN-Procurement-768x771.png 768w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/PN-Procurement-65x65.png 65w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/PN-Procurement-225x226.png 225w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/PN-Procurement-350x351.png 350w, https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/PN-Procurement.png 1010w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/><figcaption id=\"caption-attachment-1493\" class=\"wp-caption-text\">Illustration of a 2-in-1 PN procurement. A double lumen catheter has a y-connector leading to two bags: 1. amino acids, dextrose, electrolytes, vitamins and minerals; 2. Lipid.<\/figcaption><\/figure>\n<p>Some hospitals have a pre-determined <strong>standardized formulary<\/strong> for ease of ordering and preparing PN. The pre-determined formulas are all named and vary in macronutrient volumes. Additives are individualized based on patients\u2019 needs. The RD chooses the solution which closely matches the patient\u2019s requirements. <em>Here is an example of a standardized bag order form: <a href=\"http:\/\/pressbooks.library.ryerson.ca\/dietmods\/wp-content\/uploads\/sites\/262\/2021\/08\/Sample-PN-Formulary.pdf\">Sample PN Formulary (PDF).<\/a><\/em><\/p>\n<p>Some hospitals have <strong>individualized formulas<\/strong> which are prepared for a specific patient. If the hospital has a variety of solutions available, the RD can customize the PN formula to very closely match a patient\u2019s estimated requirements. If there is a limited number of solutions, the PN formula may not be ideal to meet each estimated requirement.<\/p>\n<p>It is possible that some <span style=\"font-size: 1em\">hospitals may have both standardized and individualized formularies. If a standardized formula is not appropriate, the RD would calculate a custom solution.<\/span><\/p>\n<h1><span class=\"ez-toc-section\" id=\"PN_Administration\"><\/span>PN Administration<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p>When a patient is started on PN, it g<span style=\"font-size: 1em\">enerally takes about 2 &#8211; 4 days to achieve goal volumes while monitoring metabolic tolerance.\u00a0 <\/span><span style=\"font-size: 1em\">However, this may differ for specific patients:<\/span><\/p>\n<ul>\n<li>Patients who are very malnourished or show signs and symptoms of refeeding syndrome may take up to 7 days to safely receive goal volumes. <span style=\"font-size: 1em\">Electrolytes, fluid and dextrose may need several steps of adjustment before a patient receives their goal <\/span><span style=\"text-align: initial;font-size: 1em\">nutrition<\/span><span style=\"font-size: 1em\"> provision.<\/span><\/li>\n<li>For patients who have diabetes or elevated blood glucose levels, it may take several days to adjust the patient&#8217;s insulin regime for acceptable glycemic control.<\/li>\n<\/ul>\n<p>It is common for r<span style=\"text-align: initial;font-size: 1em\">outine bloodwork to be drawn to monitor metabolic tolerance pre-PN and day 1, 2, 3 after starting PN. Typically after a patient has been stable on their goal volume of PN, bloodwork is drawn once or twice a week according to the institution&#8217;s protocol (unless the patient\u2019s medical condition requires a different monitoring schedule). <\/span><\/p>\n<p><span style=\"text-align: initial;font-size: 1em\">When starting PN, it is<\/span><span style=\"font-size: 1em\"> usually given over 24 hours. <\/span><span style=\"font-size: 1em\">Patients who require long-term PN have their delivery cycled to fewer hours to provide freedom from the IV pump\/pole and improve quality of life (QOL). PN would be given over 20 hours a day, followed by 16 hours a day, followed by 12 hours a day.\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<div class=\"textbox textbox--exercises\">\n<header class=\"textbox__header\">\n<h2 class=\"textbox__title\"><span class=\"ez-toc-section\" id=\"Poppys_Parenteral_Regime_Formula_Selection\"><\/span>Poppy&#8217;s Parenteral Regime: Formula Selection<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<\/header>\n<div class=\"textbox__content\">\n<div class=\"textbox\">\n<p><strong>Take note of Poppy\u2019s estimated requirements:<\/strong><\/p>\n<ul>\n<li>Weight: 63 kg<\/li>\n<li>Energy:\u00a0 1575-1890 kcals\/day<\/li>\n<li>Protein: 76-95 g\/day<\/li>\n<li>Fluid: very conservative<\/li>\n<\/ul>\n<\/div>\n<p>The first step in determining Poppy\u2019s parenteral plan is to select a solution. As mentioned, depending on your hospital, you will have access to different amino acid, dextrose and lipid solutions. In this case, we have access to a 5% amino acid solution, and varying dextrose solutions of 10%, 16.6%, and 25%. You can determine the energy content of each TPN solution by calculating the gram amount of amino acid and dextrose in 1L of solution. Depending on your patients needs, you can select a less or more concentrated solution.<\/p>\n<div class=\"textbox\">\n<p><strong>Pause and consider which of the solutions you would choose, based on Poppy\u2019s requirements<\/strong>:<\/p>\n<ol>\n<li style=\"list-style-type: upper-alpha\">5% amino acid (aa) + <strong>10% dextrose<\/strong> (dex)\n<ul>\n<li>50 g aa \u00d7 4 kcal\/g = 200 kcal<\/li>\n<li>100 g dex \u00d7 3.4 kcal\/g = 340 kcal<\/li>\n<li>1 L TPN = 540 kcal<\/li>\n<\/ul>\n<\/li>\n<li style=\"list-style-type: upper-alpha\">5% amino acid + <strong>16.6% dextrose<\/strong>\n<ul>\n<li>50 g aa \u00d7 4 kcal\/g = 200 kcal<\/li>\n<li>166 g dex \u00d7 3.4 kcal\/g = 564 kcal<\/li>\n<li>1 L TPN = 764 kcal<\/li>\n<\/ul>\n<\/li>\n<li style=\"list-style-type: upper-alpha\">5% amino acid + <strong>25% dextrose<\/strong>\n<ul>\n<li>50 g aa \u00d7 4 kcal\/g = 200 kcal<\/li>\n<li>250 g dex \u00d7 3.4 kcal\/g =\u00a0 850 kcal<\/li>\n<li>1 L TPN = 1050 kcal<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n<\/div>\n<p>When starting\u00a0 to work through your patient&#8217;s parenteral nutrition plan, it is common to start with calculating protein requirements. Clinicians use various methods to calculate a PN regime, however protein requirements are often a key factor and it is important to meet the patients needs. Therefore, it is suggested that you start by determining a solution that meets Poppy&#8217;s estimated protein requirements to avoid redoing\u00a0 your calculations multiple times.<\/p>\n<p><strong>Protein calculations<\/strong><\/p>\n<ul>\n<li>76 g needed \u00f7 50 g (in 1 L) = <strong>need 1.52 bags<\/strong> = 1.52 L<\/li>\n<li>1.52 L = 50 g aa \u00d7 1.52 = 76 g pro \u00d7 4 kcal\/g = 304 kcal<\/li>\n<\/ul>\n<p style=\"padding-left: 40px\">If Poppy requires a minimum of 76 g of protein per day, this would require 1.52 L of TPN using a 5% amino acid solution. <em>Protein will contribute 304 calories.<\/em><\/p>\n<p><strong>Carbohydrate calculations<\/strong><\/p>\n<ul>\n<li>100 g dex \u00d7 1.52 = 152 g CHO \u00d7 3.4 kcal\/g = 517 kcal<\/li>\n<li><strong>166 g dex \u00d7 1.52 = 252 g CHO \u00d7 3.4 kcal\/g = 859 kcal<\/strong><\/li>\n<li>250 g dex \u00d7 1.52 = 380 g CHO \u00d7 3.4 kcal\/g = 1292 kcal<\/li>\n<\/ul>\n<p style=\"padding-left: 40px\">Based on Poppy&#8217;s needs, it is reasonable to choose the 16.6% dextrose solution.<strong><br \/>\n<\/strong><em>This dextrose solution will contribute 859 calories in 1.52 L of the solution<\/em>.<\/p>\n<p><strong style=\"text-align: initial;font-size: 1em\">Lipid calculations<\/strong><\/p>\n<ul>\n<li><span style=\"font-size: 1em\">Determine calories from lipid: 1700 kcal\/day = 1700 \u2212 (304 from protein + 859 from CHO) = <\/span><strong style=\"font-size: 1em\">537 kcal needed from 20% lipid<\/strong><\/li>\n<li>Determine mL of lipid: 537 kcal\/2 kcal\/mL (20%) = 269 mL 20% lipid<\/li>\n<li>Determine grams of lipid: 537 kcal\/10 kcal\/g = 54 g lipid<\/li>\n<\/ul>\n<p style=\"padding-left: 40px\">In this case, we want to have a greater caloric contribution from lipid because Poppy\u2019s fluid requirements are restricted. Including a higher amount of lipid results in a more fluid restricted solution as lipids are calorically dense.<br \/>\n<em style=\"text-align: initial;font-size: 1em\">Poppy will receive 537 calories from lipid to meet her needs of approximately 1700 calories a day from TPN.<\/em><\/p>\n<p><span style=\"text-align: initial;font-size: 1em\">Practice these calculations and review the answers.<\/span><\/p>\n<\/div>\n<\/div>\n<div>\n<div class=\"textbox textbox--exercises\">\n<header class=\"textbox__header\">\n<h2 class=\"textbox__title\"><span class=\"ez-toc-section\" id=\"Poppys_Parenteral_Regime_Summary_of_Formula_Selection\"><\/span>Poppy&#8217;s Parenteral Regime: Summary of Formula Selection<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<\/header>\n<div class=\"textbox__content\">\n<p>Here is a summary of the formula based on 5% amino acid, 16.6% dextrose, 20% SMOFlipid and standard electrolytes.<\/p>\n<p><strong>The total amount of fluid is 1789 mL to meet Poppy\u2019s energy needs of 1700 calories a day. <\/strong><\/p>\n<p>Keep in mind that you would have need to liaise with the physicians on your team to approve the fluid volume of your TPN order as they have requested that you minimize Poppy&#8217;s fluid intake.<\/p>\n<div class=\"textbox\">\n<p>5% amino acid \/ 16.6% dextrose + 20% SMOFlipid + standard electrolytes + MVI<\/p>\n<ul>\n<li>1.52 L 5% amino acid \/ 16.6% dextrose\n<ul>\n<li>76 g pro \/ 304 kcal<\/li>\n<li>252 g CHO \/ 859 kcal<\/li>\n<\/ul>\n<\/li>\n<li>269 mL 20% SMOFlipid\n<ul>\n<li>54 g fat \/ 537 kcal<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><strong>Total<\/strong>: 1789 mL (1520 mL dextrose and AA + 269 mL lipid) \/ 1700 kcal<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<\/div>\n<h1><span class=\"ez-toc-section\" id=\"Macronutrient_Tolerance_and_Distribution\"><\/span>Macronutrient Tolerance and Distribution<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<div>After creating your PN regime, it is important to make sure your plan aligns with the guidelines for macronutrient tolerance and distribution. Pause and try calculating the macronutrient tolerance and distribution of your selected formula before moving on.<\/div>\n<div>\n<table class=\"grid\" style=\"border-collapse: collapse;width: 100%;height: 126px\">\n<caption>Macronutrient tolerance and distribution<\/caption>\n<tbody>\n<tr style=\"height: 17px\">\n<td style=\"width: 0.993049%;height: 17px\"><\/td>\n<th style=\"width: 30.5661%;height: 17px\" scope=\"col\">Macronutrient tolerance<\/th>\n<th style=\"width: 28.4409%;height: 17px\" scope=\"col\">Macronutrient distribution<\/th>\n<\/tr>\n<tr style=\"height: 19px\">\n<th style=\"width: 0.993049%;height: 19px\" scope=\"row\">Dextrose<\/th>\n<td style=\"width: 30.5661%;height: 19px\">&lt; 4-5 mg\/kg\/min<\/td>\n<td style=\"width: 28.4409%;height: 19px\">45 &#8211; 65%<\/td>\n<\/tr>\n<tr style=\"height: 54px\">\n<th style=\"width: 0.993049%;height: 54px\" scope=\"row\">Lipid<\/th>\n<td style=\"width: 30.5661%;height: 54px\">\u2264 2.0-2.5 g\/kg\/day (&lt;1.5 g\/kg\/day preferred) or &lt; 30% of daily kcal<\/td>\n<td style=\"width: 28.4409%;height: 54px\">10 &#8211; 35%<\/td>\n<\/tr>\n<tr style=\"height: 36px\">\n<th style=\"width: 0.993049%;height: 36px\" scope=\"row\">Protein<\/th>\n<td style=\"width: 30.5661%;height: 36px\">As per estimated requirements<\/td>\n<td style=\"width: 28.4409%;height: 36px\">10 &#8211; 35%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div>\n<div class=\"textbox textbox--exercises\">\n<header class=\"textbox__header\">\n<h2 class=\"textbox__title\"><span class=\"ez-toc-section\" id=\"Poppys_Parenteral_Regime_Macronutrients\"><\/span>Poppy\u2019s Parenteral Regime: Macronutrients<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<\/header>\n<div class=\"textbox__content\">\n<div class=\"textbox\">\n<p><strong>Poppy\u2019s Estimated Requirements<\/strong><\/p>\n<ul>\n<li>Weight: 63 kg<\/li>\n<li>Energy:\u00a0 1575-1890 kcal\/day<\/li>\n<li>Protein: 76-95 g\/day<\/li>\n<li>Fluid: very conservative<\/li>\n<\/ul>\n<\/div>\n<div><strong>Macronutrient tolerance<\/strong><\/div>\n<ul>\n<li>Protein as per estimated requirements: 76 g\/63 kg = 1.2 g\/kg<\/li>\n<li>Lipid \u2264 2.0-2.5 g\/kg\/day: 54 g fat\/63 kg = 0.86 g\/kg<\/li>\n<li>Dextrose \u2264 4-5 mg\/kg\/min:\n<ul>\n<li>252 g dextrose = 252000 mg<\/li>\n<li>252000 mg\/63 kg\/1440 min = 2.8 mg\/kg\/min<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<div>\n<p>For macronutrient tolerance, protein is 1.2 g\/kg which is appropriate on initiation but may need to be adjusted depending on Poppy\u2019s clinical status. Poppy would be receiving 0.86 g\/kg of lipid, and 2.8 mg\/kg\/min of dextrose which is within the guidelines for macronutrient tolerance. In this case, the formula remains appropriate for Poppy.<\/p>\n<p><strong>Macronutrient distribution<\/strong><\/p>\n<ul>\n<li>Protein = 304 kcal \u00f7 1700 kcal \u00d7 100 = 18%<\/li>\n<li>Carbohydrate = 859 kcal \u00f7 1700 kcal \u00d7 100 = 51%<\/li>\n<li>Fat = 537 kcal \u00f7 1700 kcal \u00d7 100 = 32%<\/li>\n<\/ul>\n<p>The macronutrient distribution of Poppy&#8217;s PN solution is 18% protein, 51% carbohydrate, and 32% fat \u2014 all are within the recommended ranges.\u00a0 The amount of protein Poppy will be receiving is on the lower end of the range and the amount of fat she will be receiving is on the higher end of the range. This is acceptable as a limited number of PN solutions are available on our formulary and we are working to meet Poppy&#8217;s estimated protein requirements and limit total fluid volume. As fat is calorically dense we elected to increase her proportion of fat intake to reduce fluid intake. As with any nutrition care plan , Poppy&#8217;s estimated nutrition requirements will be re-evaluated periodically based on her clinical status and her PN solution may change.<\/p>\n<p><strong>Rate of Administration<\/strong><\/p>\n<ul>\n<li>5% amino acid + 16.6% dextrose: 1.52 L = 1520 mL \u00f7 24 hrs = 63 mL\/hour<\/li>\n<li>20% lipid: 269 mL \u00f7 12 hours = 22 mL\/hour<\/li>\n<li>TFI: 1520 + 269 mL = 1789 mL\/day (28mL\/kg)<\/li>\n<\/ul>\n<p>The last step when planning a parenteral nutrition regime is to calculate the rate of administration. Poppy will receive her &#8220;2 in 1&#8221; solution of amino acids and dextrose (plus additives) at 63 mL\/hour and lipids at 11 mL\/hour. This results in 1789 mL\/day of fluid, which is 28 mL\/kg. The ICU <span class=\"ILfuVd\"><span class=\"hgKElc\">intensivist<\/span><\/span> has approved this fluid volume.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<h1><span class=\"ez-toc-section\" id=\"Initiating_PN_Refeeding_Syndrome\"><\/span>Initiating PN &amp; Refeeding Syndrome<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<div>\n<p>When your patient is at risk of refeeding syndrome, you should:<\/p>\n<ul>\n<li>Initiate feeding as soon as possible<\/li>\n<li>Determine caloric and protein requirements using current weight<\/li>\n<li>Start nutrition slowly via<span>\u00a0<\/span><strong>continuous infusion<\/strong><\/li>\n<\/ul>\n<\/div>\n<ul>\n<li><strong>Energy:<\/strong><span>\u00a0<\/span>no more than 50% of energy requirements in the first 24 hours, maximum 15-20 kcal\/kg (if at severe risk: \u226410 kcal\/kg).<\/li>\n<li><strong>Carbohydrate:<\/strong><span>\u00a0<\/span>&lt;150 g\/day or &lt; 2 mg\/kg\/minute.\u00a0Consider<span>\u00a0<\/span>all sources<span>\u00a0<\/span>of carbohydrates (dextrose containing IV fluids, oral intake, medications).<\/li>\n<li><strong>Protein:<\/strong><span>\u00a0<\/span>start at the goal of requirements up to 1.5 g\/kg.<\/li>\n<li><strong>Supplementation:<\/strong><span>\u00a0<\/span>daily multivitamin and 100 mg thiamine \u00d7 3 days.<\/li>\n<li><strong>Obtain bloodwork:<\/strong><span>\u00a0<\/span>replace low electrolyte levels (prior to initiating feeding, 4-6 hours after initiating feeding, and daily for minimum 5 days).<\/li>\n<\/ul>\n<\/div>\n<div>\n<div class=\"textbox textbox--exercises\">\n<header class=\"textbox__header\">\n<h2 class=\"textbox__title\"><span class=\"ez-toc-section\" id=\"Poppys_Parenteral_Regime_Refeeding_Syndrome\"><\/span>Poppy&#8217;s Parenteral Regime: Refeeding Syndrome<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<\/header>\n<div class=\"textbox__content\">\n<p>As per our assessment, Poppy is at low-moderate risk of refeeding syndrome.<\/p>\n<p>Despite the refeeding risk, PN is initiated conservatively to assess metabolic tolerance. The conservative start typically meets the requirements for safely starting nutrition support when a patient is at risk of refeeding syndrome.<\/p>\n<p>Request thiamine and multivitamin supplementation for patients who are at risk.<\/p>\n<\/div>\n<\/div>\n<h1><span class=\"ez-toc-section\" id=\"Summary_of_Nutrition_Plan\"><\/span>Summary of Nutrition Plan<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<div class=\"textbox textbox--exercises\">\n<header class=\"textbox__header\">\n<h2 class=\"textbox__title\"><span class=\"ez-toc-section\" id=\"Summary_of_Poppys_Nutrition_Care_Plan\"><\/span>Summary of Poppy\u2019s Nutrition Care Plan<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<\/header>\n<div class=\"textbox__content\">\n<table class=\"grid\" style=\"height: 289px\">\n<caption><span>Summary of recommendations for Poppy\u2019s nutrition care plan<\/span><\/caption>\n<tbody>\n<tr style=\"height: 17px\">\n<th style=\"height: 17px;width: 109.328px\" scope=\"col\">Area of Concern<\/th>\n<th style=\"height: 17px;width: 558.062px\" scope=\"col\">Recommendations<\/th>\n<\/tr>\n<tr style=\"height: 119px\">\n<td style=\"height: 119px;width: 109.328125px\">Parenteral Nutrition<\/td>\n<td style=\"height: 119px;width: 558.0625px\">\n<ul>\n<li>5% amino acid + 16.6% dextrose: 1.52 L = 63 mL\/hour x 24 hours (PRO 18%, CHO 51%)<\/li>\n<li>20% lipid: 269 mL= 22 mL\/hour x 12 hours (FAT 32%)<\/li>\n<li>TFI: 1520 + 269 mL = 1789 mL\/day (28 mL\/kg)- volume approved by MD<\/li>\n<li>Initiate slowly at ~ 50% of poppy&#8217;s requirements<\/li>\n<li>Monitor closely for refeeding and PN complications \u2013 see implementation section<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr style=\"height: 51px\">\n<td style=\"height: 51px;width: 109.328125px\">Medications and Infusions<\/td>\n<td style=\"height: 51px;width: 558.0625px\">\n<ul>\n<li>NS @ 10 mL\/hour = 240 mL\/day<\/li>\n<li>Ongoing diuresis (furosemide): monitor fluid balance and urine output for fluid overload; adjust nutrition care plan if indicated<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr style=\"height: 34px\">\n<td style=\"height: 34px;width: 109.328125px\">Laboratory Values<\/td>\n<td style=\"height: 34px;width: 558.0625px\">\n<ul>\n<li>Monitor electrolytes and hemodynamic stability daily<\/li>\n<li>Sodium slightly low (132) \u2013 monitor<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr style=\"height: 51px\">\n<td style=\"height: 51px;width: 109.328125px\">Supplements<\/td>\n<td style=\"height: 51px;width: 558.0625px\">\n<ul>\n<li>Add a daily multivitamin for risk of refeeding syndrome<\/li>\n<li>Add 100 mg thiamine \u00d7 3 days when initiating PN due to risk of refeeding syndrome<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr style=\"height: 17px\">\n<td style=\"height: 17px;width: 109.328125px\">Diet<\/td>\n<td style=\"height: 17px;width: 558.0625px\">\n<ul>\n<li>NPO \u2013 re: doctors orders and intolerance to EN<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<h1><span class=\"ez-toc-section\" id=\"Simulation_Activity_Poppy\"><\/span>Simulation Activity: Poppy<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<div id=\"h5p-64\">\n<div class=\"h5p-iframe-wrapper\"><iframe id=\"h5p-iframe-64\" class=\"h5p-iframe\" data-content-id=\"64\" style=\"height:1px\" src=\"about:blank\" frameBorder=\"0\" scrolling=\"no\" title=\"Simulation for Parenteral Nutrition\"><\/iframe><\/div>\n<\/div>\n<div class=\"textbox shaded\">\n<p>PART 2: PLAN COMPLETE. Pause to reflect on the nutrition care plan we created for Poppy. When you\u2019re ready, move on to Part 3: Implementation.<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<\/div>\n<div><\/div>\n","protected":false},"author":315,"menu_order":3,"template":"","meta":{"pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":""},"chapter-type":[],"contributor":[],"license":[],"class_list":["post-152","chapter","type-chapter","status-publish","hentry"],"part":110,"_links":{"self":[{"href":"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-json\/pressbooks\/v2\/chapters\/152","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-json\/wp\/v2\/users\/315"}],"version-history":[{"count":39,"href":"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-json\/pressbooks\/v2\/chapters\/152\/revisions"}],"predecessor-version":[{"id":2440,"href":"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-json\/pressbooks\/v2\/chapters\/152\/revisions\/2440"}],"part":[{"href":"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-json\/pressbooks\/v2\/parts\/110"}],"metadata":[{"href":"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-json\/pressbooks\/v2\/chapters\/152\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-json\/wp\/v2\/media?parent=152"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-json\/pressbooks\/v2\/chapter-type?post=152"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-json\/wp\/v2\/contributor?post=152"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/pressbooks.library.torontomu.ca\/dietmods\/wp-json\/wp\/v2\/license?post=152"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}